Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | MGAM | O43451 | 9/20 | 0.46 |
| ▸ | GAA | P10253 | 9/20 | 0.46 |
| ▸ | SI | P14410 | 9/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10252888 | 0.84 | NPC1 (0.64) | S1PR4MGAMGAASIMGAM2 | |
| SCHEMBL881750 | 0.81 | NPC1 (0.64) | S1PR4MGAMGAASIMGAM2 | |
| SCHEMBL10286990 | 0.77 | NPC1 (0.67) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL10287172 | 0.72 | RAB9A (0.39) | GAAMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL27623968 | 0.72 | S1PR4 (0.58) | S1PR4GAAMEN1MAPTKMT2A | |
| SCHEMBL24073708 | 0.70 | KDR (0.64) | MEN1KMT2AALDH1A1TP53NPC1 | |
| SCHEMBL375593 | 0.68 | S1PR4 (0.57) | S1PR4MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL10286992 | 0.67 | KMT2A (0.57) | MEN1MAPTKMT2AALDH1A1TP53 | |
| SCHEMBL19632762 | 0.67 | STAT3 (0.61) | GAAMEN1KMT2AALDH1A1TP53 | |
| SCHEMBL27135218 | 0.67 | CYP1A2 (0.55) | MEN1MAPTKMT2AALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010187-A1 | BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010187-A1 | BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS | NMT1, MLEC, EPN1 | S1PR4 4787/4885MGAM 1009/4885GAA 3124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.