Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 15/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952593 | 0.95 | PI4KA (0.47) | PI4KAPIK3CGCYP11B2TNKSCCNC | |
| Formic Acid SCHEMBL9954566 | 0.83 | PI4KA (0.47) | PI4KAPIK3CGCYP11B2 | |
| SCHEMBL10288787 | 0.78 | PI4KA (0.50) | PI4KAPIK3CGCYP11B2 | |
| SCHEMBL9954693 | 0.76 | PIM1 (0.46) | PI4KAPIK3CGCYP11B2 | |
| SCHEMBL9954049 | 0.75 | PI4KA (0.53) | PI4KAPIK3CG | |
| SCHEMBL10288780 | 0.75 | PI4KA (0.52) | PI4KAPIK3CG | |
| SCHEMBL9953679 | 0.75 | PI4KA (0.51) | PI4KAPIK3CGCYP11B2 | |
| SCHEMBL9954428 | 0.73 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9955619 | 0.73 | PI4KA (0.56) | PI4KAPIK3CGCYP11B2 | |
| SCHEMBL9953943 | 0.72 | PI4KA (0.59) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |