Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10291725 | 0.86 | POLB (0.62) | CCR1PTPN1CYP2C9CYP2C19KDM4E | |
| SCHEMBL10291735 | 0.86 | CCR1 (0.65) | CCR1POLBKCNH2 | |
| SCHEMBL14434315 | 0.86 | POLB (0.59) | CCR1PTPN1CYP2C9CYP2C19KDM4E | |
| SCHEMBL10291634 | 0.74 | CCR1 (0.60) | CCR1KCNH2 | |
| SCHEMBL25443739 | 0.74 | SLC9A1 (0.46) | CCR1PTPN1CYP2C9CYP2C19KDM4E | |
| SCHEMBL14749038 | 0.74 | KDM4E (0.50) | PTPN1CYP2C9CYP2C19KDM4EPOLB | |
| SCHEMBL14672010 | 0.73 | HRH3 (0.56) | CCR1CYP2C9CYP2C19KDM4EPOLB | |
| SCHEMBL15686707 | 0.72 | EPHX2 (0.60) | CCR1KCNH2HRH3ALDH1A1EPHX2 | |
| SCHEMBL12321681 | 0.71 | NAMPT (0.60) | PTPN1KDM4EALDH1A1NAMPT | |
| SCHEMBL15840473 | 0.71 | ADAMTS5 (0.58) | POLBKCNH2HRH3ALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471774-A1 | Piperidinyl derivatives as modulators of chemokine receptor activity | Bristol-Myers Squibb Company (US) | 2012-07-04 | — | — | EP | disclosed |