Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14752079 | 0.84 | EPHX2 (0.45) | KMT2ASLC9A1BCHEEPHX2 | |
| SCHEMBL12193639 | 0.78 | ALDH1A1 (0.53) | KDM4EKMT2AALDH1A1MEN1GAA | |
| SCHEMBL389894 | 0.77 | KDM4E (0.56) | KDM4EKMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL23865988 | 0.76 | NOS2 (0.60) | KDM4EKMT2AALDH1A1MEN1GAA | |
| SCHEMBL21987051 | 0.75 | ALDH1A1 (0.40) | KDM4ECYP2C9CYP2C19KMT2AALDH1A1 | |
| SCHEMBL20744332 | 0.75 | — | — | |
| SCHEMBL18711444 | 0.75 | CPT2 (0.49) | KDM4ECYP2C9CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL23865987 | 0.75 | CYP3A4 (0.51) | CYP2C9CYP2C19ALDH1A1BCHE | |
| SCHEMBL10291725 | 0.74 | POLB (0.62) | KDM4ECYP2C9CYP2C19PTPN1ALDH1A1 | |
| SCHEMBL14434315 | 0.74 | POLB (0.59) | KDM4ECYP2C9CYP2C19PTPN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200046745-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2020-02-13 | — | — | US | disclosed |
| US-20130059803-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200046745-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | KDM4E 4323/4885CYP2C9 4785/4885CYP2C19 4831/4885 |
| US-20130059803-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | KDM4E 3418/4885CYP2C9 2019/4885CYP2C19 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.