Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15459716 | 0.92 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL16301325 | 0.90 | DGAT1 (0.42) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL10293053 | 0.89 | PTPN1 (0.42) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL10292676 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL15459679 | 0.84 | RAB9A (0.42) | ALDH1A1TSHRTDP1DGAT1SOAT1 | |
| SCHEMBL10292876 | 0.84 | PTPN1 (0.38) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL16301294 | 0.82 | DGAT1 (0.46) | KDM4EALDH1A1HSD17B10TP53TSHR | |
| SCHEMBL15459715 | 0.80 | ATR (0.36) | KDM4EALDH1A1PTPN1GAAMAPT | |
| SCHEMBL15765677 | 0.80 | PTPN11 (0.44) | KDM4EMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL15459714 | 0.79 | ATR (0.36) | KDM4EALDH1A1PTPN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691120-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2014-04-08 | — | — | US | disclosed |
| EP-2479171-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120170098-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120170098-A1 | CHROMENE COMPOUND | CRY2, CRY1, SUN2 | KDM4E 3632/4885ALDH1A1 2266/4885HSD17B10 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.