Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16841255 | 1.00 | HRH3 (0.45) | HRH3HRH4KDM4ELMNARAB9A | |
| SCHEMBL3538083 | 1.00 | HRH3 (0.45) | HRH3HRH4KDM4ELMNARAB9A | |
| SCHEMBL12124997 | 1.00 | HRH3 (0.45) | HRH3HRH4KDM4ELMNARAB9A | |
| SCHEMBL835259 | 0.88 | — | — | |
| SCHEMBL24662658 | 0.83 | HRH4 (0.34) | HRH3HRH4KDM4ELMNARAB9A | |
| SCHEMBL14367704 | 0.83 | HRH4 (0.34) | HRH3HRH4KDM4ELMNARAB9A | |
| SCHEMBL13179767 | 0.83 | HRH4 (0.34) | HRH3HRH4KDM4ELMNARAB9A | |
| SCHEMBL27171710 | 0.83 | HRH4 (0.34) | HRH3HRH4 | |
| SCHEMBL24123700 | 0.83 | HRH4 (0.34) | HRH3HRH4 | |
| SCHEMBL21230458 | 0.82 | KDM4E (0.35) | HRH3HRH4KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843551-A | Organic-inorganic hybrid crystal with photoluminescence characteristics, and preparation method and application thereof | 东南大学 | 2024-04-09 | — | — | CN | claimed |
| CN-105314646-B | AEI type Si-Al molecular sieves and its preparation method and application | 南京开丽环保材料有限公司 | 2018-06-08 | — | — | CN | claimed |
| CN-105314646-A | AEI-type aluminosilicate molecular sieves, and preparation methods and applications thereof | SUN HONG | 2016-02-10 | — | — | CN | claimed |
| CN-105315195-A | Template agent and preparation method therefor and application thereof | SUN HONG | 2016-02-10 | — | — | CN | claimed |
| WO-2025125027-A1 | METHOD FOR SYNTHESISING AN IZM-10 AEI ZEOLITE HAVING A VERY HIGH PURITY IN THE PRESENCE OF A NITROGEN-CONTAINING ORGANIC STRUCTURING AGENT | IFP Energies Nouvelles (FR) | 2025-06-19 | — | — | WO | disclosed |
| WO-2025125026-A1 | SYNTHESIS OF A CATALYST COMPRISING AN IZM-10 AEI ZEOLITE AND AT LEAST ONE TRANSITION METAL FOR THE SELECTIVE REDUCTION OF NOX | IFP Energies Nouvelles (FR) | 2025-06-19 | — | — | WO | disclosed |
| CN-117843551-A | Organic-inorganic hybrid crystal with photoluminescence characteristics, and preparation method and application thereof | 东南大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117843551-A | Organic-inorganic hybrid crystal with photoluminescence characteristics, and preparation method and application thereof | 东南大学 | 2024-04-09 | — | — | CN | disclosed |
| WO-2024052556-A1 | A PROCESS FOR THE ACTIVATION OF N2O IN THE PRESENCE OF A ZEOLITIC MATERIAL HAVING THE AEI-TYPE FRAMEWORK STRUCTURE | BASF SE (DE) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024017884-A1 | PROCESS FOR THE CATALYTIC ACTIVATION OF N2O | BASF SE (DE) | 2024-01-25 | — | — | WO | disclosed |
| US-11649214-B2 | Inhibitors of the notch transcriptional activation complex kinase (“NACK”) and methods for use of the same | UNIVERSITY OF MIAMI (US) | 2023-05-16 | — | — | US | disclosed |
| US-20210171469-A1 | INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX KINASE (\"NACK\") AND METHODS FOR USE OF THE SAME | UNIVERSITY OF MIAMI | 2021-06-10 | — | — | US | disclosed |
| US-20090075979-A1 | CETP Inhibitors | MERCK SHARP & DOHME LLC | 2009-03-19 | — | — | US | disclosed |
| US-20090054407-A1 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20090054407-A1 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20080227793-A1 | Benzimidazole and Pyridylimidazole Derivatives | NEUROGEN CORPORATION | 2008-09-18 | — | — | US | disclosed |
| WO-2008098239-A2 | PARAMYXOVIRUS FAMILY INHIBITORS AND METHODS OF USE THEREOF | EMORY UNIVERSITY (US) | 2008-08-14 | — | — | WO | disclosed |
| US-7342115-B2 | Binding antagonist and arylpyridine for antiinflammatory agents, cardiovascular disorders and antagonist or agonist and for immunology | NEUROGEN CORPORATION (US) | 2008-03-11 | — | — | US | disclosed |
| US-7300945-B2 | Benzimidazole and pyridylimidazole derivatives | NEUROGEN CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |
| US-7247617-B2 | Sixteen-member macrolide antiinfective agents | KOSAN BIOSCIENCES INCORPORATED (US) | 2007-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075979-A1 | CETP Inhibitors | CETP, APOB, MTTP | HRH3 1212/4885HRH4 1724/4885KDM4E 1388/4885 |
| US-20080227793-A1 | Benzimidazole and Pyridylimidazole Derivatives | GABBR1, GABBR2, GABRA2 | HRH3 87/4885HRH4 96/4885KDM4E 1996/4885 |
| US-20090054407-A1 | Nitrogen-containing heterocyclic compound | NR4A1, NR5A2, PRMT8 | HRH3 229/4885HRH4 45/4885KDM4E 488/4885 |
| US-20210171469-A1 | INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX KINASE (\"NACK\") AND METHODS FOR USE OF THE SAME | CHUK, NOTCH1, NUAK1 | HRH3 3570/4885HRH4 4066/4885KDM4E 1027/4885 |
| US-11649214-B2 | Inhibitors of the notch transcriptional activation complex kinase (“NACK”) and methods for use of the same | NOTCH1, CHUK, CBFB | HRH3 3629/4885HRH4 4080/4885KDM4E 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.