SCHEMBL1029385

SCHEMBL1029385

Cc1ccc2c(S(=O)(=O)O)ccc(O)c2n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
OPRK1 P41145 1/20 0.59
COMT P21964 4/20 0.55
CTSB P07858 1/20 0.53
CTSH P09668 1/20 0.53
METAP2 P50579 1/20 0.43
FTO Q9C0B1 2/20 0.41
TNNI3 P19429 1/20 0.39
TNNT2 P45379 1/20 0.39
TNNC1 P63316 1/20 0.39
HKDC1 Q2TB90 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 1/20 0.39
ALOX15 P16050 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.38
NSD2 O96028 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11316137 0.89 COMT (0.76) KMT2AOPRK1COMTFTOALDH1A1
SCHEMBL4764600 0.87 MAPT (0.56) KMT2AOPRK1COMTCTSBCTSH
SCHEMBL27638396 0.85 OPRK1 (0.57) KMT2AOPRK1COMTCTSBCTSH
SCHEMBL30961312 0.83 OPRK1 (0.54) KMT2AOPRK1COMTCTSBCTSH
SCHEMBL3898406 0.82 AURKA (0.43) KMT2AOPRK1COMTCTSBCTSH
SCHEMBL24716067 0.80 COMT (0.55) KMT2AOPRK1COMTFTOTNNI3
SCHEMBL11811488 0.80 COMT (0.55) KMT2AOPRK1COMTFTOTNNI3
SCHEMBL4764607 0.79 KDM4E (0.41) KMT2AOPRK1COMTCTSBCTSH
SCHEMBL3275602 0.78 KMT2A (0.77) KMT2AOPRK1CTSBCTSHMETAP2
SCHEMBL9471001 0.78 COMT (0.53) KMT2ACOMTFTOTNNI3TNNT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0061444-A4 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS. UNION OIL CO (US) 1983-02-04 EP claimed
EP-0061444-A1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS. UNION OIL CO (US) 1982-10-06 EP claimed
WO-1982001364-A1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS UNION OIL CO (US) 1982-04-29 WO claimed
US-4283379-A WASHING SOLUTION OF SOLUBILIZED VANADIUM, WATER SOLUBLE NONQUINONE AROMATIC COMPOUNDS, THIOCYANATE IONS, AND A CARBOXYLATE COMPLEXING AGENT UNION OIL COMPANY OF CALIFORNIA (US) 1981-08-11 US claimed
EP-4623914-A1 USE OF 8-HYDROXYQUINOLINE DERIVATIVE Jiangsu Yahong Meditech Co., Ltd. (CN) 2025-10-01 EP disclosed
CN-120035438-A Use of 8-hydroxyquinoline derivatives 江苏亚虹医药科技股份有限公司 2025-05-23 CN disclosed
US-20240246916-A1 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF JIANGSU YAHONG MEDITECH CO., LTD. (CN) 2024-07-25 US disclosed
WO-2024109684-A1 USE OF 8-HYDROXYQUINOLINE DERIVATIVE 江苏亚虹医药科技股份有限公司 2024-05-30 WO disclosed
CN-118059101-A Use of 8-hydroxyquinoline derivatives 江苏亚虹医药科技股份有限公司 2024-05-24 CN disclosed
EP-4349815-A1 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2024-04-10 EP disclosed
CN-117043141-A 7-nitro-8-hydroxyquinoline derivative, preparation method and medical application thereof 江苏亚虹医药科技股份有限公司 2023-11-10 CN disclosed
WO-2022253152-A1 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 江苏亚虹医药科技股份有限公司 2022-12-08 WO disclosed
EP-1904482-A2 INDOLYLMALEIMIDE DERIVATIVES Novartis AG (CH) 2008-04-02 EP disclosed
WO-2007006533-A2 INDOLYLMALEIMIDE DERIVATIVES NOVARTIS AG (CH) 2007-01-18 WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
EP-0061444-B1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS UNION OIL COMPANY OF CALIFORNIA (US) 1985-05-22 EP disclosed
EP-0061444-A4 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS. UNION OIL CO (US) 1983-02-04 EP disclosed
EP-0061444-A1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS. UNION OIL CO (US) 1982-10-06 EP disclosed
WO-1982001364-A1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS UNION OIL CO (US) 1982-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246916-A1 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF CYP3A7, UGT1A7, UGT2B7 KMT2A 2738/4885OPRK1 1364/4885COMT 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.