Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10294744 | 0.88 | SMN1; SMN2 (0.51) | SMN1; SMN2GAAMAPTRAF1DDR1 | |
| SCHEMBL13753114 | 0.87 | ALDH1A1 (0.64) | L3MBTL1ALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL21538013 | 0.86 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL25469569 | 0.84 | TRPV1 (0.47) | ALDH1A1GAAMAPTKMT2ANPC1 | |
| SCHEMBL6361446 | 0.84 | GAA (0.73) | L3MBTL1ALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL13753863 | 0.82 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL10294124 | 0.82 | NPC1 (0.54) | ALDH1A1POLBSMN1; SMN2MAPTKMT2A | |
| SCHEMBL1490845 | 0.81 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL14336245 | 0.81 | ALDH1A1 (0.64) | L3MBTL1ALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL8386465 | 0.81 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1POLBSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172361-A1 | TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CALIFORNIA CAPITAL EQUITY, LLC (US) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172361-A1 | TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CYP3A5, CYP11B2, ABCB1 | L3MBTL1 4542/4885ALDH1A1 213/4885POLB 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.