Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14943806 | 1.00 | LMNA (0.33) | LMNACYP2D6 | |
| SCHEMBL15759764 | 0.91 | LMNA (0.30) | LMNACYP2D6 | |
| SCHEMBL12063910 | 0.89 | LMNA (0.38) | LMNACYP2D6 | |
| SCHEMBL27119879 | 0.89 | — | — | |
| SCHEMBL10295987 | 0.87 | — | — | |
| SCHEMBL19880109 | 0.76 | POLB (0.32) | — | |
| SCHEMBL1100489 | 0.76 | LMNA (0.35) | LMNACYP2D6 | |
| SCHEMBL22383985 | 0.74 | — | — | |
| SCHEMBL23504662 | 0.73 | LMNA (0.33) | LMNACYP2D6 | |
| SCHEMBL25920321 | 0.73 | LMNA (0.33) | LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172449-A1 | POLYAMINE TRANSPORT INHIBITORS AS NOVEL THERAPEUTICS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172449-A1 | POLYAMINE TRANSPORT INHIBITORS AS NOVEL THERAPEUTICS | SLC19A1, SLC75A1, SLC46A1 | LMNA 4553/4885CYP2D6 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.