Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219618 | 0.79 | HSD17B10 (1.00) | HSD17B10OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL7587764 | 0.79 | HSD17B10 (1.00) | HSD17B10OPRK1OPRL1OPRM1OPRD1 | |
| Ammonia Solution, Strong SCHEMBL1764035 | 0.78 | HSD17B10 (0.97) | HSD17B10OPRK1OPRL1OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL6160546 | 0.78 | HSD17B10 (0.97) | HSD17B10OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL11878938 | 0.78 | HSD17B10 (0.70) | HSD17B10OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL7842659 | 0.78 | HSD17B10 (0.70) | HSD17B10OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL3863096 | 0.76 | HSD17B10 (0.67) | HSD17B10OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL3863396 | 0.75 | HSD17B10 (0.65) | HSD17B10OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL13543072 | 0.73 | HSD17B10 (0.55) | HSD17B10OPRK1OPRL1OPRM1OPRD1 | |
| SCHEMBL23256393 | 0.72 | ITGB3 (0.60) | HSD17B10HTR1AHTR2CADRB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898962-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | Bracco Imaging, S.P.A. (IT) | 2008-03-19 | — | — | EP | claimed |
| WO-2007002500-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2007-01-04 | — | — | WO | claimed |
| EP-2291075-A2 | GASTRIN RELEASING PEPTIDE COMPOUNDS | Bracco Imaging S.p.A (IT) | 2011-03-09 | — | — | EP | disclosed |
| EP-2274328-A1 | PEPTIDES, PEPTIDOMIMETICS AND DERIVATIVES THEREOF, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION | Fibrex Medical Research & Development GmbH (AT) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009143101-A2 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009137850-A1 | PEPTIDES, PEPTIDOMIMETICS AND DERIVATIVES THEREOF, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION | FIBREX MEDICAL RESEARCH & DEVELOPMENT GMBH (AT) | 2009-11-19 | — | — | WO | disclosed |