Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.55 |
| ▸ | HTR3B | O95264 | 2/20 | 0.55 |
| ▸ | HTR3A | P46098 | 2/20 | 0.55 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.55 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880373 | 0.86 | ITGB3 (0.64) | ITGB3ITGA2BUSP2ALDH1A1HSD17B10 | |
| SCHEMBL15682617 | 0.83 | HTR7 (0.50) | ITGB3ITGA2BHTR7HTR1AADRB1 | |
| SCHEMBL5238923 | 0.83 | HTR7 (0.50) | ITGB3ITGA2BHTR7HTR1AADRB1 | |
| SCHEMBL4577325 | 0.83 | ADRB1 (0.55) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL6583384 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BSIGMAR1CYP2C9CYP2C19 | |
| SCHEMBL20425007 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BHTR1ASIGMAR1HTR6 | |
| SCHEMBL3204004 | 0.81 | HTR7 (0.60) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL4541029 | 0.81 | ITGB3 (0.59) | ITGB3ITGA2BADRB1HTR3EHTR3B | |
| SCHEMBL28739636 | 0.81 | ITGB3 (0.62) | ITGB3ITGA2BHTR1ASIGMAR1HTR6 | |
| Hydrochloric Acid SCHEMBL6409641 | 0.80 | HTR7 (0.58) | HTR7HTR1AADRB1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10987351-B2 | RORgamma modulators and uses thereof | GENFIT (FR) | 2021-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10987351-B2 | RORgamma modulators and uses thereof | RORB, RORC, RORA | ITGB3 1439/4885ITGA2B 862/4885HTR7 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.