SCHEMBL10296309

SCHEMBL10296309

C=C(C)OC(=O)N1CCC(CCCCc2ccc(N[S+](C)[O-])cc2)CC1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.40
GPR119 Q8TDV5 13/20 0.38
NMT1 P30419 2/20 0.38
CNR2 P34972 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MGLL Q99685 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10296272 0.87 SMN1; SMN2 (0.43) FAAHGPR119CNR2KDM4EALDH1A1
SCHEMBL10296248 0.83 FAAH (0.42) FAAHGPR119NMT1KDM4EALDH1A1
SCHEMBL13462415 0.82 GPR119 (0.55) GPR119NMT1
SCHEMBL13462347 0.79 SMN1; SMN2 (0.47) FAAHALDH1A1MGLL
SCHEMBL13462348 0.78 NAMPT (0.46) FAAHKDM4EALDH1A1MGLL
SCHEMBL10296266 0.77 GPR119 (0.49) GPR119ALDH1A1
SCHEMBL1575459 0.73 PTPN2 (0.54) GPR119
SCHEMBL1575330 0.73 GPR119 (0.53) FAAHGPR119KDM4E
SCHEMBL1575460 0.72 PTPN2 (0.65) GPR119
SCHEMBL1575684 0.71 GPR119 (0.53) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120172358-A1 GPCR Agonists PROSIDION LIMITED (GB) 2012-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172358-A1 GPCR Agonists GPR119, GCGR, GPR27 FAAH 295/4885GPR119 1/4885NMT1 1642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.