Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | NMT1 | P30419 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10296272 | 0.86 | SMN1; SMN2 (0.43) | FAAHKDM4EALDH1A1GPR119 | |
| SCHEMBL13462415 | 0.86 | GPR119 (0.55) | GPR119NMT1 | |
| SCHEMBL1575563 | 0.84 | GPR119 (0.54) | FAAHKDM4EALDH1A1GPR119 | |
| SCHEMBL10296309 | 0.83 | FAAH (0.40) | FAAHMGLLKDM4EALDH1A1GPR119 | |
| SCHEMBL4600115 | 0.80 | MAOB (0.44) | FAAHKDM4EALDH1A1OPRK1SPHK1 | |
| SCHEMBL1575127 | 0.80 | GPR119 (0.54) | FAAHKDM4EALDH1A1GPR119 | |
| SCHEMBL13462347 | 0.78 | SMN1; SMN2 (0.47) | FAAHMGLLALDH1A1 | |
| SCHEMBL13462348 | 0.77 | NAMPT (0.46) | FAAHMGLLKDM4EALDH1A1OPRK1 | |
| SCHEMBL27719507 | 0.75 | SPHK1 (0.40) | FAAHKDM4EALDH1A1GPR119OPRK1 | |
| SCHEMBL14783164 | 0.75 | FAAH (0.51) | FAAHKDM4EALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172358-A1 | GPCR Agonists | PROSIDION LIMITED (GB) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172358-A1 | GPCR Agonists | GPR119, GCGR, GPR27 | FAAH 295/4885MGLL 345/4885KDM4E 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.