3,4-Methylendioxy Acetophenone

3,4-Methylendioxy Acetophenone

SCHEMBL29405437

CC(=O)c1ccc2c(c1)OCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.71
ALDH1A1 P00352 5/20 0.69
MAPK1 P28482 1/20 0.69
KMT2A Q03164 3/20 0.69
MEN1 O00255 2/20 0.69
NPC1 O15118 4/20 0.68
RAB9A P51151 4/20 0.68
MAPT P10636 4/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
PKM P14618 1/20 0.62
NFKB1 P19838 1/20 0.62
NFKB2 Q00653 1/20 0.62
RELA Q04206 1/20 0.62
SRD5A2 P31213 1/20 0.61
TSHR P16473 1/20 0.59
HPGD P15428 3/20 0.57
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4-Methylendioxy Acetophenone SCHEMBL137979 1.00 KDM4E (0.71) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL102971 0.88 KDM4E (0.89) KDM4EKMT2AMEN1NPC1RAB9A
SCHEMBL16369468 0.86 KDM4E (0.54) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL31574502 0.85 GABRA1 (0.61) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL4097987 0.85 GABRA1 (0.61) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL13596352 0.85 KDM4E (0.77) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL3735582 0.85 KDM4E (0.77) KDM4EALDH1A1KMT2ANPC1RAB9A
3,4-Methylendioxy Acetophenone SCHEMBL31108909 0.85 KDM4E (0.67) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL12930765 0.85 MEN1 (0.75) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL4824941 0.83 SRD5A2 (0.82) ALDH1A1MAPK1KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081871-A Quinoline compound and preparation method and application thereof 江西农业大学 2025-06-03 CN claimed
CN-119954819-A Quinoline compound, preparation method and agricultural application thereof 江西农业大学 2025-05-09 CN claimed
CN-116041212-A Preparation and application of difluoro olefin ether and oxime ether derivatives 安徽农业大学 2023-05-02 CN claimed
CN-114105971-A 6- (benzo 1,3 dioxopentacyclyl) -4 phenyl-6H-1, 3-thiazine-2-amine derivative and application thereof 南京林业大学 2022-03-01 CN claimed
EP-4658656-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
WO-2025215121-A1 HEDGEHOG ACYLTRANSFERASE INHIBITORS IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-10-16 WO disclosed
CN-116041212-B Preparation and application of difluoro olefin oxime ether derivative 安徽农业大学 2025-06-13 CN disclosed
CN-120081871-A Quinoline compound and preparation method and application thereof 江西农业大学 2025-06-03 CN disclosed
CN-119954819-A Quinoline compound, preparation method and agricultural application thereof 江西农业大学 2025-05-09 CN disclosed
CN-117402170-B Quinoline compound and preparation method and application thereof 江西农业大学 2025-05-06 CN disclosed
CN-119930469-A Chalcone compound containing alpha, beta-unsaturated hydroxamic acid groups and preparation method and application thereof 河北医科大学 2025-05-06 CN disclosed
CN-118666857-B Quinoline compound and application thereof in agricultural bactericides 江西农业大学 2025-02-25 CN disclosed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
CN-116041212-A Preparation and application of difluoro olefin ether and oxime ether derivatives 安徽农业大学 2023-05-02 CN disclosed
EP-4061807-A1 NOVEL COMPOUNDS FOR THE DIAGNOSIS, TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH THE AGGREGATION OF ALPHA-SYNUCLEIN Modag GmbH (DE) 2022-09-28 EP disclosed
CN-110627610-B Method for synthesizing alkyne by catalyzing asymmetric cross coupling 南方科技大学 2022-07-05 CN disclosed
WO-2022133303-A1 COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS THE SCRIPPS RESEARCH INSTITUTE (US) 2022-06-23 WO disclosed
CN-110198946-B Compound, substrate for pattern formation, photodegradable coupling agent, pattern formation method, and method for manufacturing transistor 株式会社尼康 2022-04-26 CN disclosed
WO-2022044000-A1 DESALINATION OF WATER USING A COMPLEXING AGENT ATTACHED TO A MAGNETIC NANOPARTICLE N W P T - NANO WATER PURIFICATION TECHNOLOGY LTD (IL) 2022-03-03 WO disclosed
CN-114105971-A 6- (benzo 1,3 dioxopentacyclyl) -4 phenyl-6H-1, 3-thiazine-2-amine derivative and application thereof 南京林业大学 2022-03-01 CN disclosed