3,4-Methylendioxy Acetophenone

3,4-Methylendioxy Acetophenone

SCHEMBL137979

CC(=O)c1ccc2c(c1)OCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.71
ALDH1A1 P00352 5/20 0.69
MAPK1 P28482 1/20 0.69
KMT2A Q03164 3/20 0.69
MEN1 O00255 2/20 0.69
NPC1 O15118 4/20 0.68
RAB9A P51151 4/20 0.68
MAPT P10636 4/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
PKM P14618 1/20 0.62
NFKB1 P19838 1/20 0.62
NFKB2 Q00653 1/20 0.62
RELA Q04206 1/20 0.62
SRD5A2 P31213 1/20 0.61
TSHR P16473 1/20 0.59
HPGD P15428 3/20 0.57
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4-Methylendioxy Acetophenone SCHEMBL29405437 1.00 KDM4E (0.71) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL102971 0.88 KDM4E (0.89) KDM4EKMT2AMEN1NPC1RAB9A
SCHEMBL16369468 0.86 KDM4E (0.54) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL31574502 0.85 GABRA1 (0.61) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL4097987 0.85 GABRA1 (0.61) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL13596352 0.85 KDM4E (0.77) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL3735582 0.85 KDM4E (0.77) KDM4EALDH1A1KMT2ANPC1RAB9A
3,4-Methylendioxy Acetophenone SCHEMBL31108909 0.85 KDM4E (0.67) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL12930765 0.85 MEN1 (0.75) KDM4EALDH1A1MAPK1KMT2AMEN1
SCHEMBL4824941 0.83 SRD5A2 (0.82) ALDH1A1MAPK1KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 909 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039135-A Carboxyl chalcone derivative and preparation method and application thereof 四川大学 2024-11-29 CN claimed
CN-115925527-B Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2024-02-09 CN claimed
CN-113522294-B Ni-based catalyst, preparation method thereof and application thereof in reductive amination 中国科学院青岛生物能源与过程研究所 2023-08-29 CN claimed
CN-116041212-A Preparation and application of difluoro olefin ether and oxime ether derivatives 安徽农业大学 2023-05-02 CN claimed
CN-115999537-A Porous composite oxide encapsulated metal catalyst and preparation method and application thereof 中国科学院青岛生物能源与过程研究所 2023-04-25 CN claimed
CN-111116375-B Method for preparing primary amine by catalyzing aldehyde ketone compound through reductive amination 中国科学院广州能源研究所 2023-04-07 CN claimed
CN-115925527-A Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2023-04-07 CN claimed
CN-114105971-A 6- (benzo 1,3 dioxopentacyclyl) -4 phenyl-6H-1, 3-thiazine-2-amine derivative and application thereof 南京林业大学 2022-03-01 CN claimed
CN-113831328-A 6- (benzo 1,3 dioxygen pentacyl) -4 phenyl pyrimidine amide derivative and preparation method and application thereof 南京林业大学 2021-12-24 CN claimed
CN-113563301-A Synthesis process of 3, 4-methylenedioxyphenol 绵阳三香汇生物科技有限公司 2021-10-29 CN claimed
US-20030059681-A1 Polymeric sol electrolyte and lithium battery using the same SAMSUNG SDI CO., LTD. (KR) 2003-03-27 US claimed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO claimed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed