Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL484049 | 0.91 | TP53 (0.35) | MAPTESR1ESR2LMNAPKM | |
| SCHEMBL5242548 | 0.83 | TSHR (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5824636 | 0.81 | TPMT (0.46) | CA1CA2PDPK1PTPN1 | |
| SCHEMBL572232 | 0.81 | CES2 (0.48) | MAPTLMNAHPGDCA1CA2 | |
| SCHEMBL20258185 | 0.81 | NOS3 (0.44) | MAPTLMNAHPGDNPC1RAB9A | |
| SCHEMBL2318580 | 0.81 | CES2 (0.48) | MAPTLMNAHPGDHTTCA1 | |
| SCHEMBL2892447 | 0.81 | ALDH1A1 (0.48) | MAPTLMNAPKMHPGDHTT | |
| SCHEMBL199868 | 0.81 | CES2 (0.48) | MAPTLMNACA1CA2CES2 | |
| SCHEMBL24728745 | 0.80 | CES1 (0.44) | MAPTLMNAHPGDCA1CA2 | |
| SCHEMBL8396 | 0.80 | CES1 (0.44) | MAPTLMNAHPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2008530-B1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | SYMRISE AG (DE) | 2011-01-19 | — | — | EP | claimed |