SCHEMBL67894

SCHEMBL67894

O=[C]OCc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 6/20 0.42
KDM4E B2RXH2 5/20 0.42
HPGD P15428 5/20 0.40
HSD17B10 Q99714 4/20 0.40
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 4/20 0.38
CYP1A1 P04798 2/20 0.38
CYP1B1 Q16678 2/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
POLB P06746 2/20 0.37
GLA P06280 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901166 0.80 KMT2A (0.50) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL3767629 0.78 HPRT1 (0.47) KMT2AMEN1ALDH1A1HSD17B10TSHR
SCHEMBL15082603 0.77 KMT2A (0.45) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL2121863 0.77 KMT2A (0.51) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL29852 0.77 TDP1 (0.47) KMT2AMEN1ALDH1A1HPGDTDP1
SCHEMBL9815022 0.77 ALDH1A1 (0.48) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL2939780 0.77 KMT2A (0.47) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL2939781 0.77 KMT2A (0.47) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL8927201 0.76 KMT2A (0.47) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL67895 0.76 KMT2A (0.47) KMT2AMEN1ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130052690-A1 PCR PRIMER AND METHOD FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION USING A PHOTOLABILE PROTECTING GROUP SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-02-28 US claimed
US-8246754-B2 Process for removing ink from printed substrate HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2012-08-21 US claimed
US-7087732-B2 Nucleotides and analogs having photoremovable protecting groups AFFYMETRIX, INC. (US) 2006-08-08 US claimed
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides STEALTH BIOTHERAPEUTICS INC. (US) 2024-07-16 US disclosed
US-20240158400-A1 SYNTHESIS OF A BRUTON'S TYROSINE KINASE INHIBITOR PHARMACYCLICS LLC (US) 2024-05-16 US disclosed
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF STEALTH BIOTHERAPEUTICS INC. (US) 2024-04-04 US disclosed
US-20240092799-A1 MNK INHIBITORS HEPAGENE THERAPEUTICS HK LTD (CN) 2024-03-21 US disclosed
US-11708374-B2 Preparation of condensed triazepine derivatives and their use as BET inhibitors Worg Pharmaceuticals (Zhejiang) Co., Ltd. (CN) 2023-07-25 US disclosed
CN-116490505-A MNK inhibitors 和博医药有限公司 2023-07-25 CN disclosed
EP-4200296-A1 MNK INHIBITORS Hepagene Therapeutics (HK) Limited (HK) 2023-06-28 EP disclosed
US-20230092024-A1 Increasing Efficiency Of Photochemical Reactions On Substrates CENTRILLION TECHNOLOGIES, INC. 2023-03-23 US disclosed
WO-1994006808-A1 METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS AFFYMAX TECHNOLOGIES N.V. (AN) 1994-03-31 WO disclosed
EP-0562025-A4 1994-03-30 EP disclosed
US-5288514-A Linking a protected 2-aminobenzophenone to a substrate; deprotecting and reacting with an amino acid; cyclization; removal from substrate; screening THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-02-22 US disclosed
US-5252743-A Using cage binding compound AFFYMAX TECHNOLOGIES N.V. (NL) 1993-10-12 US disclosed
EP-0562025-A1 VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS AFFYMAX TECHNOLOGIES N.V. (AN) 1993-09-29 EP disclosed
EP-0502060-A4 SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES 1993-05-05 EP disclosed
EP-0502060-A1 SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES AFFYMAX TECHNOLOGIES N.V. (AN) 1992-09-09 EP disclosed
WO-1992010092-A1 VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS AFFYMAX TECHNOLOGIES N.V. (AN) 1992-06-25 WO disclosed
WO-1991007087-A1 SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES AFFYMAX TECHNOLOGIES N.V. (AN) 1991-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130052690-A1 PCR PRIMER AND METHOD FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION USING A PHOTOLABILE PROTECTING GROUP POLL, POLRMT, POLN KMT2A 1919/4885MEN1 2119/4885ALDH1A1 1877/4885
US-20240092799-A1 MNK INHIBITORS MKNK1, MATK, NEK1 KMT2A 443/4885MEN1 713/4885ALDH1A1 4526/4885
US-20230092024-A1 Increasing Efficiency Of Photochemical Reactions On Substrates TYR, PCNA, DNMT1 KMT2A 1427/4885MEN1 3754/4885ALDH1A1 1455/4885
US-12037414-B2 Processes for preparing pharmaceutically relevant peptides ADM2, VIP, PEPD KMT2A 767/4885MEN1 194/4885ALDH1A1 4638/4885
US-20240158400-A1 SYNTHESIS OF A BRUTON'S TYROSINE KINASE INHIBITOR BTK, ABL1, LYN KMT2A 1188/4885MEN1 3314/4885ALDH1A1 4045/4885
US-11708374-B2 Preparation of condensed triazepine derivatives and their use as BET inhibitors BET1, EP300, BICRA KMT2A 292/4885MEN1 920/4885ALDH1A1 4080/4885
US-20240108740-A1 THERAPEUTIC COMPOSITIONS INCLUDING SPN10 AND USES THEREOF S100A10, SPG11, TMSB10 KMT2A 4440/4885MEN1 3607/4885ALDH1A1 4705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.