SCHEMBL10299698

SCHEMBL10299698

Cc1ccc(C(=O)/C=C/c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.86
ALDH1A1 P00352 5/20 0.77
HPGD P15428 3/20 0.77
CYP1B1 Q16678 2/20 0.77
CYP3A4 P08684 2/20 0.77
MAOB P27338 5/20 0.75
MAOA P21397 4/20 0.75
POLB P06746 1/20 0.75
RAB9A P51151 1/20 0.75
XDH P47989 1/20 0.69
CYP1A1 P04798 1/20 0.67
HTT P42858 3/20 0.62
NPSR1 Q6W5P4 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
PKM P14618 2/20 0.62
ATM Q13315 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
LMNA P02545 2/20 0.62
NLRP1 Q9C000 1/20 0.62
MEN1 O00255 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8480932 1.00 MAPT (0.86) MAPTALDH1A1HPGDCYP1B1CYP3A4
SCHEMBL8480925 1.00 MAPT (0.86) MAPTALDH1A1HPGDCYP1B1CYP3A4
SCHEMBL25194931 1.00 MAPT (0.86) MAPTALDH1A1HPGDCYP1B1CYP3A4
4,4'-Dimethylchalcone SCHEMBL979559 0.93 MAPT (1.00) MAPTALDH1A1HPGDCYP1B1CYP3A4
4,4'-Dimethylchalcone SCHEMBL979560 0.93 MAPT (1.00) MAPTALDH1A1HPGDCYP1B1CYP3A4
SCHEMBL2997295 0.91 XDH (0.74) MAPTALDH1A1HPGDCYP1B1CYP3A4
SCHEMBL25195971 0.91 XDH (0.74) MAPTALDH1A1HPGDCYP1B1CYP3A4
SCHEMBL25201250 0.91 XDH (0.74) MAPTALDH1A1HPGDCYP1B1CYP3A4
SCHEMBL2997293 0.91 XDH (0.74) MAPTALDH1A1HPGDCYP1B1CYP3A4
SCHEMBL10528715 0.91 XDH (0.74) MAPTALDH1A1HPGDCYP1B1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-20170152443-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-01 US disclosed
US-20170022419-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-01-26 US disclosed
US-8399068-B2 Liquid crystal aligning agent, method of producing a liquid crystal alignment film and liquid crystal display device JSR CORPORATION (JP) 2013-03-19 US disclosed
US-8304031-B2 Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display device JSR CORPORATION (JP) 2012-11-06 US disclosed
US-8216649-B2 Liquid crystal aligning agent, method of producing a liquid crystal alignment film and liquid crystal display device JSR CORPORATION (JP) 2012-07-10 US disclosed
US-20110118422-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD OF PRODUCING A LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2011-05-19 US disclosed
US-20110105700-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2011-05-05 US disclosed
US-20110068301-A1 LIQUID CRYSTAL ALIGNING AGENT, METHOD OF PRODUCING A LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885ALDH1A1 3285/4885HPGD 939/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885ALDH1A1 3081/4885HPGD 542/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885ALDH1A1 3081/4885HPGD 542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.