SCHEMBL103011

SCHEMBL103011

C1=NC(c2ccccn2)CCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 2/20 0.40
DDB1 Q16531 1/20 0.37
CRBN Q96SW2 1/20 0.37
MAPT P10636 3/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
CYP1A2 P05177 2/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35
CCR8 P51685 1/20 0.35
METAP1 P53582 1/20 0.35
BLM P54132 1/20 0.35
HIF1A Q16665 1/20 0.35
DOHH Q9BU89 1/20 0.35
P4HTM Q9NXG6 1/20 0.35
GRM5 P41594 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4245966 0.77 DDB1 (0.31) ALDH1A1KDM4EDDB1CRBN
SCHEMBL1171264 0.74 ALDH1A1 (0.41) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL3389545 0.73 NOS1 (0.46) ALDH1A1CYP1A2LMNABLM
SCHEMBL449107 0.73 ALDH1A1 (0.44) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL3154131 0.71 ALDH1A1 (0.43) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL7447299 0.69
SCHEMBL1481510 0.69 ALDH1A1 (0.50) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL1515110 0.69 ALDH1A1 (0.46) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL290575 0.68 TAAR1 (0.42) ALDH1A1DDB1CRBNLMNA
SCHEMBL161142 0.68 ALDH1A1 (0.40) ALDH1A1KDM4EDDB1CRBNMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274922-A2 A CASCADE CO2 ELECTROREDUCTION SYSTEM AND RELATED METHODS FOR ENHANCED PRODUCTION OF ETHYLENE TOTALENERGIES ONETECH (FR) 2023-11-15 EP claimed
WO-2022148837-A2 A CASCADE CO2 ELECTROREDUCTION SYSTEM AND RELATED METHODS FOR ENHANCED PRODUCTION OF ETHYLENE TOTALENERGIES ONETECH (FR) 2022-07-14 WO claimed
CN-114555620-A Novel galactoside inhibitors of galectins 格莱克特生物技术公司 2022-05-27 CN claimed
EP-0226319-A1 Electrochemical dimerizations of pyridinium salts REILLY INDUSTRIES, INC. (US) 1987-06-24 EP claimed
CN-119799606-A Recombinant escherichia coli for producing heme and derivative compound thereof and preparation method thereof 微元合成生物技术(北京)有限公司 2025-04-11 CN disclosed
US-20240044021-A1 A CASCADE CO2 ELECTROREDUCTION SYSTEM AND RELATED METHODS FOR ENHANCED PRODUCTION OF ETHYLENE THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2024-02-08 US disclosed
EP-4274922-A2 A CASCADE CO2 ELECTROREDUCTION SYSTEM AND RELATED METHODS FOR ENHANCED PRODUCTION OF ETHYLENE TOTALENERGIES ONETECH (FR) 2023-11-15 EP disclosed
US-11746426-B2 Stabilization of a co-bound intermediate via molecular tuning promotes CO2-to-ethylene conversion CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-09-05 US disclosed
WO-2022148837-A2 A CASCADE CO2 ELECTROREDUCTION SYSTEM AND RELATED METHODS FOR ENHANCED PRODUCTION OF ETHYLENE TOTALENERGIES ONETECH (FR) 2022-07-14 WO disclosed
CN-114555620-A Novel galactoside inhibitors of galectins 格莱克特生物技术公司 2022-05-27 CN disclosed
WO-2021007508-A9 THE STABILIZATION OF A CO-BOUND INTERMEDIATE VIA MOLECULAR TUNING PROMOTES CO2-TO-ETHYLENE CONVERSION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2021-11-18 WO disclosed
US-20210062349-A1 STABILIZATION OF A CO-BOUND INTERMEDIATE VIA MOLECULAR TUNING PROMOTES CO2-TO-ETHYLENE CONVERSION THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2021-03-04 US disclosed
US-6509351-B1 A method of inhibiting TNF- alpha in a patient in need thereof which comprises administering to said patient an effective amount of a compound for inflamation SANOFI-SYNTELABO (FR) 2003-01-21 US disclosed
CN-1391570-A Phenyl-and pyridyl-tetrahydro-pyridines having TNF inhibiting activity SANOFI SYNTHELABO (FR) 2003-01-15 CN disclosed
US-20020193405-A1 Thiazolyl urea compounds and methods of uses AMGEN INC. 2002-12-19 US disclosed
WO-2002085888-A1 TETRAHYDROPYRIDYL-ALKYL-HETEROCYCLES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SANOFI-SYNTHELABO (FR) 2002-10-31 WO disclosed
EP-0226319-B1 ELECTROCHEMICAL DIMERIZATIONS OF PYRIDINIUM SALTS REILLY INDUSTRIES, INC. (US) 1991-08-07 EP disclosed
EP-0226319-A1 Electrochemical dimerizations of pyridinium salts REILLY INDUSTRIES, INC. (US) 1987-06-24 EP disclosed
US-4670111-A Electrochemical dimerizations of pyridinium salts REILLY TAR & CHEMICAL CORP. (US) 1987-06-02 US disclosed
US-3886172-A METALLIZATION, CONDENSATION ICI LTD 1975-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193405-A1 Thiazolyl urea compounds and methods of uses SLC14A1, UMPS, BAX ALDH1A1 810/4885KDM4E 2714/4885DDB1 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.