Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248383 | 1.00 | ALOX5 (0.54) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL6248378 | 1.00 | ALOX5 (0.54) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL180118 | 0.85 | SLC1A3 (0.54) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL1663153 | 0.85 | SLC1A3 (0.54) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL599915 | 0.85 | SLC1A3 (0.54) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL12240912 | 0.84 | ALDH1A1 (0.50) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL10926891 | 0.84 | ALDH1A1 (0.50) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL25284288 | 0.83 | ALOX5 (0.51) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL27949190 | 0.83 | ALOX5 (0.51) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6530727 | 0.82 | ALOX5 (0.47) | ALOX5SLC1A3SLC1A2SLC1A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053279-B2 | Methods for the site-selective coupling of a first agent to a second agent | UNIVERSITEIT GENT (BE) | 2021-07-06 | — | — | US | disclosed |
| EP-3313858-B1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIV GENT (BE) | 2019-09-25 | — | — | EP | disclosed |
| US-20190002494-A1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIVERSITEIT GENT (BE) | 2019-01-03 | — | — | US | disclosed |
| EP-2481407-A1 | Compounds for use in treating cognitive disorders | Allergan, Inc. (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2474534-A1 | 3-Aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds having analgesic and/or immunostimulant activity | Allergan, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053279-B2 | Methods for the site-selective coupling of a first agent to a second agent | PAICS, HNMT, DPYD | ALOX5 554/4885SLC1A3 4248/4885SLC1A2 2293/4885 |
| US-20190002494-A1 | METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT | PAICS, HNMT, DPYD | ALOX5 554/4885SLC1A3 4248/4885SLC1A2 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.