SCHEMBL1663153

SCHEMBL1663153

N[C@H](Cc1ccco1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.54
SLC1A2 P43004 2/20 0.54
SLC1A1 P43005 2/20 0.54
SLC7A5 Q01650 3/20 0.53
PKM P14618 2/20 0.53
PTGS1 P23219 2/20 0.53
ALPI P09923 1/20 0.53
XIAP P98170 1/20 0.53
ALOX5 P09917 1/20 0.50
POLB P06746 1/20 0.44
PTPN1 P18031 1/20 0.44
PTPN7 P35236 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
ESR2 Q92731 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 1/20 0.44
ALDH1A1 P00352 1/20 0.43
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599915 1.00 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1SLC7A5PKM
SCHEMBL180118 1.00 SLC1A3 (0.54) SLC1A3SLC1A2SLC1A1SLC7A5PKM
Trifluoroacetic Acid SCHEMBL4806415 0.91 GRB2 (0.50) SLC1A3SLC1A2SLC1A1SLC7A5PKM
D-Glutamate SCHEMBL29008193 0.87 SLC1A3 (0.50) SLC1A3SLC1A2SLC1A1SLC7A5PKM
SCHEMBL6248383 0.85 ALOX5 (0.54) SLC1A3SLC1A2SLC1A1ALOX5POLB
SCHEMBL6248378 0.85 ALOX5 (0.54) SLC1A3SLC1A2SLC1A1ALOX5POLB
SCHEMBL10305129 0.85 ALOX5 (0.54) SLC1A3SLC1A2SLC1A1ALOX5POLB
SCHEMBL2265386 0.85 SLC1A1 (0.59) SLC1A3SLC1A2SLC1A1ALOX5
SCHEMBL9554473 0.84 SLC7A5 (0.46) SLC1A3SLC1A2SLC1A1SLC7A5PKM
SCHEMBL12240912 0.84 ALDH1A1 (0.50) SLC1A3SLC1A2SLC1A1SLC7A5PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178836-A1 GADD45BETA TARGETING AGENTS Imperial Innovations Limited (GB) 2017-06-14 EP claimed
US-9434764-B2 Skin care compositions and methods comprising selective agonists of melanocortin 1 receptor UNIVERSITY OF CINCINNATI (US) 2016-09-06 US claimed
US-20150368294-A1 GADD45BETA TARGETING AGENTS IP2IPO INNOVATIONS LIMITED (GB) 2015-12-24 US claimed
US-20150299251-A1 Skin Care Compositions and Methods Comprising Selective Agonists of Melanocortin 1 Receptor UNIVERSITY OF CINCINNATI (US) 2015-10-22 US claimed
US-20150297667-A1 PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-10-22 US claimed
EP-2925340-A2 PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR University Of Cincinnati (US) 2015-10-07 EP claimed
EP-2922565-A2 SKIN CARE COMPOSITIONS AND METHODS COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR University Of Cincinnati (US) 2015-09-30 EP claimed
WO-2014081845-A2 SKIN CARE COMPOSITIONS AND METHODS COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR UNIVERSITY OF CINCINNATI (US) 2014-05-30 WO claimed
WO-2014081846-A2 PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR UNIVERSITY OF CINCINNATI (US) 2014-05-30 WO claimed
US-20120277164-A1 GADD45BETA TARGETING AGENTS IMPERIAL INNOVATIONS LIMITED (GB) 2012-11-01 US claimed
EP-2491051-A2 GADD45BETA TARGETING AGENTS Imperial Innovations Limited (GB) 2012-08-29 EP claimed
WO-2011048390-A2 GADD45BETA TARGETING AGENTS IMPERIAL INNOVATIONS LIMITED (GB) 2011-04-28 WO claimed
US-20250340574-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2025-11-06 US disclosed
EP-3650464-B1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND SHANGPHARMA INNOVATION INC (US) 2025-11-05 EP disclosed
EP-4545553-A2 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND ShangPharma Innovation Inc. (US) 2025-04-30 EP disclosed
EP-4504739-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Vertex Pharmaceuticals Incorporated (US) 2025-02-12 EP disclosed
US-20100261769-A1 Topical Compositions Comprising Non-Proteogenic Amino Acids and Methods of Treating Skin AVON PRODUCTS, INC. (US) 2010-10-14 US disclosed
US-20080058383-A1 Androgen Receptor Modulators KARO BIO AB (SE) 2008-03-06 US disclosed
EP-1685090-A1 ANDROGEN RECEPTOR MODULATORS KARO BIO AB (SE) 2006-08-02 EP disclosed
WO-2005042464-A1 ANDROGEN RECEPTOR MODULATORS KARO BIO AB (SE) 2005-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368294-A1 GADD45BETA TARGETING AGENTS DDB1, CCL2, DDIT3 SLC1A3 3016/4885SLC1A2 3489/4885SLC1A1 3062/4885
US-20250340574-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1G, SCNN1B SLC1A3 2879/4885SLC1A2 3321/4885SLC1A1 2485/4885
US-20100261769-A1 Topical Compositions Comprising Non-Proteogenic Amino Acids and Methods of Treating Skin LOXL1, LOXL2, LOXL3 SLC1A3 1600/4885SLC1A2 1798/4885SLC1A1 1511/4885
US-20080058383-A1 Androgen Receptor Modulators NR5A1, ESRRA, AR SLC1A3 2957/4885SLC1A2 2186/4885SLC1A1 2576/4885
US-20120277164-A1 GADD45BETA TARGETING AGENTS DDB1, CCL2, DDIT3 SLC1A3 3016/4885SLC1A2 3489/4885SLC1A1 3062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.