Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31710727 | 0.92 | ALOX5 (0.44) | MAPTALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30313121 | 0.91 | GAA (0.43) | MAPTALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8664177 | 0.90 | MAPT (0.45) | MAPTALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28566645 | 0.88 | CACNA1H (0.46) | MAPTALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8649124 | 0.87 | MAPT (0.46) | MAPTALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1019102 | 0.86 | MAPT (0.55) | MAPTALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL372131 | 0.85 | PPARG (0.51) | MAPTL3MBTL1PPARGPPARANAMPT | |
| SCHEMBL13055397 | 0.82 | KDM4A (0.51) | KDM4AL3MBTL1NAMPTCA1CA2 | |
| SCHEMBL18664385 | 0.82 | HDAC1 (0.49) | L3MBTL1PPARGPPARANAMPTCA1 | |
| SCHEMBL27262445 | 0.82 | PPARG (0.48) | MAPTRAB9AL3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006459-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2015-04-14 | — | — | US | disclosed |
| US-9006459-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2015-04-14 | — | — | US | disclosed |
| US-20150004712-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | UNIVERSITY OF OTTAWA (CA) | 2015-01-01 | — | — | US | disclosed |
| US-20150004712-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | UNIVERSITY OF OTTAWA (CA) | 2015-01-01 | — | — | US | disclosed |
| US-8835641-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2014-09-16 | — | — | US | disclosed |
| US-8835641-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20120171665-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | UNIVERSITE DE MONTREAL (CA) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171665-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | HNRNPH1, HNRNPH3, HNRNPC | MAPT 4697/4885ALOX5 3515/4885SMN1; SMN2 4074/4885 |
| US-20150004712-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | HNRNPH1, HNRNPH3, HNRNPC | MAPT 4697/4885ALOX5 3515/4885SMN1; SMN2 4074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.