Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | RRM1 | P23921 | 3/20 | 0.39 |
| ▸ | RRM2 | P31350 | 3/20 | 0.39 |
| ▸ | RRM2B | Q7LG56 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10306370 | 0.89 | LMNA (0.40) | LMNASMN1; SMN2RRM1RRM2RRM2B | |
| SCHEMBL10306371 | 0.81 | MAPT (0.52) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10306437 | 0.75 | LMNA (0.40) | LMNASMN1; SMN2RRM1RRM2RRM2B | |
| SCHEMBL17082477 | 0.73 | NPC1 (0.44) | NPC1RAB9AMAP4K4 | |
| SCHEMBL10306439 | 0.72 | LMNA (0.39) | LMNASMN1; SMN2RRM1RRM2RRM2B | |
| SCHEMBL10306369 | 0.72 | MAPT (0.52) | ALDH1A1SMN1; SMN2RRM1RRM2RRM2B | |
| SCHEMBL16401861 | 0.72 | MEN1 (0.43) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16401860 | 0.72 | MEN1 (0.43) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10306331 | 0.72 | LMNA (0.40) | LMNASMN1; SMN2RRM1RRM2RRM2B | |
| SCHEMBL1230233 | 0.71 | TLR2 (0.46) | ALDH1A1NPC1RAB9AMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-9179681-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| EP-2461687-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |
| US-20140148340-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140148340-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2014-05-29 | — | — | US | disclosed |
| US-8680269-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-8680269-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| WO-2011017504-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148340-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PLCG2 | LMNA 3489/4885ALDH1A1 2480/4885SMN1; SMN2 2109/4885 |
| US-20120172217-A1 | PESTICIDAL COMPOSITIONS | DDT, AADAC, ACHE | LMNA 3885/4885ALDH1A1 1359/4885SMN1; SMN2 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.