Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230233 | 0.89 | TLR2 (0.46) | NPC1RAB9ANLRP3TLR2TLR1 | |
| SCHEMBL2743492 | 0.83 | KIF11 (0.51) | NPC1RAB9ANLRP3TLR2TLR1 | |
| SCHEMBL1259287 | 0.83 | KIF11 (0.51) | NPC1RAB9ANLRP3TLR2TLR1 | |
| SCHEMBL1260302 | 0.80 | KIF11 (0.55) | NPC1RAB9ANLRP3TLR2TLR1 | |
| SCHEMBL1260380 | 0.77 | TLR2 (0.65) | NPC1RAB9ATLR2TLR1PTGS2 | |
| SCHEMBL29559210 | 0.76 | NPC1 (0.43) | NPC1RAB9ANLRP3TLR2TLR1 | |
| SCHEMBL29559542 | 0.75 | NR2E1 (0.44) | NPC1RAB9ANLRP3TLR2TLR1 | |
| SCHEMBL1230291 | 0.73 | SCN5A (0.40) | NPC1RAB9ANLRP3MAP4K4PSEN1 | |
| SCHEMBL10306372 | 0.73 | LMNA (0.40) | NPC1RAB9AMAP4K4 | |
| SCHEMBL1230313 | 0.72 | MAOA (0.43) | NPC1RAB9ANLRP3MAP4K4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2461687-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-09-16 | — | — | EP | disclosed |