Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15337170 | 0.88 | PPARG (0.51) | ALDH1A1TDP1CA1CA2CA12 | |
| SCHEMBL12788053 | 0.87 | ALDH1A1 (0.56) | ALDH1A1TDP1CA1CA2CA12 | |
| SCHEMBL17083281 | 0.86 | LOXL2 (0.56) | ALDH1A1TDP1CA1CA2CA12 | |
| SCHEMBL14622438 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TDP1CA1CA2CA12 | |
| SCHEMBL7718912 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TDP1CA1CA2CA12 | |
| SCHEMBL29934082 | 0.86 | LOXL2 (0.56) | ALDH1A1TDP1CA1CA2CA12 | |
| SCHEMBL17811367 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TDP1CA1CA2CA12 | |
| SCHEMBL14175211 | 0.85 | TDP1 (0.52) | ALDH1A1TDP1CA1CA2CA12 | |
| SCHEMBL13438864 | 0.85 | CA12 (0.61) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL31359375 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TDP1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227412-A1 | Substituted Benzimidazole Derivative And Use Thereof | CHENGDU FANXI BIOPHARMA CO., LTD. (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20180098952-A1 | INACTIVATORS OF TOXOPLASMA GONDII ORNITHINE AMINOTRANSFERASE FOR TREATING TOXOPLASMOSIS AND MALARIA | NORTHWESTERN UNIVERSITY (US) | 2018-04-12 | — | — | US | disclosed |
| US-9914740-B2 | Tricyclic pyrido-carboxamide derivatives as rock inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-13 | — | — | US | disclosed |
| US-20170152287-A1 | METHODS AND COMPOSITIONS FOR SITE-SPECIFIC LABELING OF PEPTIDES AND PROTEINS | UNIVERSITY OF ROCHESTER | 2017-06-01 | — | — | US | disclosed |
| US-9557336-B2 | Methods and compositions for site-specific labeling of peptides and proteins | UNIVERSITY OF ROCHESTER (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150241440-A1 | METHODS AND COMPOSITIONS FOR SITE-SPECIFIC LABELING OF PEPTIDES AND PROTEINS | NATIONAL SCIENCE FOUNDATION | 2015-08-27 | — | — | US | disclosed |
| US-20150045387-A1 | Bi-Aromatic And Tri-Aromatic Compounds As NADPH Oxidase 2 (Nox2) Inhibitors | THE UNIVERSITY OF SURREY (GB) | 2015-02-12 | — | — | US | disclosed |
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
| US-7388021-B2 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152287-A1 | METHODS AND COMPOSITIONS FOR SITE-SPECIFIC LABELING OF PEPTIDES AND PROTEINS | PTMS, ACP1, QPCTL | ALDH1A1 3945/4885TDP1 3238/4885CA1 1869/4885 |
| US-20150045387-A1 | Bi-Aromatic And Tri-Aromatic Compounds As NADPH Oxidase 2 (Nox2) Inhibitors | NOX4, CYBB, NOX1 | ALDH1A1 524/4885TDP1 1081/4885CA1 3940/4885 |
| US-20180098952-A1 | INACTIVATORS OF TOXOPLASMA GONDII ORNITHINE AMINOTRANSFERASE FOR TREATING TOXOPLASMOSIS AND MALARIA | OAT, OTC, ABAT | ALDH1A1 163/4885TDP1 1275/4885CA1 1060/4885 |
| US-20150241440-A1 | METHODS AND COMPOSITIONS FOR SITE-SPECIFIC LABELING OF PEPTIDES AND PROTEINS | PTMS, ACP1, QPCTL | ALDH1A1 3945/4885TDP1 3238/4885CA1 1869/4885 |
| US-20120178743-A1 | NOVEL ADENINE COMPOUND AND USE THEREOF | ADORA1, HRH4, P2RY10 | ALDH1A1 875/4885TDP1 3483/4885CA1 1729/4885 |
| US-20230227412-A1 | Substituted Benzimidazole Derivative And Use Thereof | PPARD, PPARG, PPARA | ALDH1A1 674/4885TDP1 1078/4885CA1 3890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.