Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.78 |
| ▸ | NPC1 | O15118 | 10/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.78 |
| ▸ | TP53 | P04637 | 4/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130390 | 0.89 | RAB9A (0.81) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL6799157 | 0.88 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL6361263 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL22192206 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL8770881 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL30341896 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL8769709 | 0.83 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL10311786 | 0.83 | NPC1 (0.68) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL12509646 | 0.82 | NPC1 (0.76) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL5333909 | 0.82 | RAB9A (0.86) | RAB9ANPC1SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120177572-A1 | AMYLOID IMAGING AS A SURROGATE MARKER FOR EFFICACY OF ANTI-AMYLOID THERAPIES | UNIVERSITY OF PITTSBURGH- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2012-07-12 | — | — | US | disclosed |
| US-20080286202-A1 | Method of Diagnosing Prodromal Forms of Diseases Associated With Amyloid Deposition | UNIVERSITY OF PITTSBURGH (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120177572-A1 | AMYLOID IMAGING AS A SURROGATE MARKER FOR EFFICACY OF ANTI-AMYLOID THERAPIES | TTR, APP, SAAL1 | RAB9A 3270/4885NPC1 332/4885SMN1; SMN2 117/4885 |
| US-20080286202-A1 | Method of Diagnosing Prodromal Forms of Diseases Associated With Amyloid Deposition | PSEN2, PSEN1, APP | RAB9A 3106/4885NPC1 109/4885SMN1; SMN2 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.