Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 5/20 | 0.34 |
| ▸ | NOS1 | P29475 | 5/20 | 0.34 |
| ▸ | NOS2 | P35228 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10058697 | 0.73 | INMT (0.86) | INMTUSP2SIGMAR1NOS3NOS1 | |
| SCHEMBL6038391 | 0.71 | INMT (0.91) | INMTUSP2SIGMAR1NOS3NOS1 | |
| SCHEMBL2742282 | 0.71 | INMT (0.91) | INMTUSP2SIGMAR1NOS3NOS1 | |
| SCHEMBL496207 | 0.71 | INMT (0.91) | INMTUSP2SIGMAR1NOS3NOS1 | |
| SCHEMBL2956216 | 0.71 | INMT (0.91) | INMTUSP2SIGMAR1NOS3NOS1 | |
| SCHEMBL5475300 | 0.71 | INMT (0.91) | INMTUSP2SIGMAR1NOS3NOS1 | |
| SCHEMBL3270217 | 0.71 | INMT (0.91) | INMTUSP2SIGMAR1NOS3NOS1 | |
| SCHEMBL219036 | 0.71 | INMT (0.91) | INMTUSP2SIGMAR1NOS3NOS1 | |
| SCHEMBL20718625 | 0.71 | INMT (0.91) | INMTUSP2SIGMAR1NOS3NOS1 | |
| SCHEMBL6859113 | 0.71 | INMT (0.91) | INMTUSP2SIGMAR1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | disclosed |