Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31650493 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL18227206 | 0.87 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL18237754 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL10312334 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL10453840 | 0.83 | ALDH1A1 (0.96) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL19755165 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL14150586 | 0.82 | MAPK1 (0.65) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL9577143 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL21048464 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL12672471 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828879-B2 | Silicon-containing composition having sulfonamide group for forming resist underlayer film | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20120178261-A1 | SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178261-A1 | SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM | STS, SI, MUS81 | ALDH1A1 2958/4885KDM4E 115/4885LMNA 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.