SCHEMBL1031262

SCHEMBL1031262

CCN(CC)c1cccc(C=Cc2ccccc2)c1[N+](=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 2/20 0.44
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPT P10636 3/20 0.42
LMNA P02545 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
THRB P10828 1/20 0.42
PTBP1 P26599 1/20 0.42
ALDH3A1 P30838 1/20 0.42
HPGD P15428 1/20 0.41
POLB P06746 1/20 0.41
CYP19A1 P11511 3/20 0.40
TRPM8 Q7Z2W7 1/20 0.39
FBP1 P09467 1/20 0.39
HTT P42858 2/20 0.38
TP53 P04637 1/20 0.38
HCAR3 P49019 1/20 0.38
NPC1 O15118 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1005683 0.86 NFE2L2 (0.46) NFE2L2MEN1KMT2AALDH1A1MAPT
SCHEMBL10478158 0.81 ALDH3A1 (0.50) MEN1KMT2AALDH1A1MAPTLMNA
SCHEMBL9009256 0.80 ALDH3A1 (0.42) MEN1KMT2AALDH1A1MAPTLMNA
SCHEMBL3186646 0.80 ALDH1A1 (0.50) NFE2L2MEN1KMT2AALDH1A1MAPT
SCHEMBL11206645 0.78 NFE2L2 (0.47) NFE2L2MEN1KMT2AALDH1A1MAPT
SCHEMBL11206640 0.78 NFE2L2 (0.47) NFE2L2MEN1KMT2AALDH1A1MAPT
SCHEMBL1031259 0.77 ALDH1A1 (0.56) MEN1KMT2AALDH1A1MAPTLMNA
SCHEMBL7260787 0.76 MAPT (0.53) NFE2L2MEN1KMT2AMAPTKDM4E
SCHEMBL2112646 0.75 NFE2L2 (0.63) NFE2L2ALDH1A1CYP19A1
SCHEMBL3247450 0.75 NFE2L2 (0.63) NFE2L2ALDH1A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722095-B2 Fluorescent nanocrystals encapsulated in an inorganic shell Centre National de la Recherche Scientifique—CNRS (FR) 2014-05-13 US claimed
EP-2260085-B1 FLUORESCENT NANOCRYSTALS ENCAPSULATED IN AN INORGANIC SHELL CENTRE NAT RECH SCIENT (FR) 2012-10-03 EP claimed
EP-2125992-B1 FLUORESCENT ORGANIC NANOCRYSTALS FOR PRODUCING BIOSENSORS CENTRE NAT RECH SCIENT (FR) 2012-09-12 EP claimed
US-20110110864-A1 FLUORESCENT NANOCRYSTALS ENCAPSULATED IN AN INORGANIC SHELL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS- (FR) 2011-05-12 US claimed
EP-2260085-A1 FLUORESCENT NANOCRYSTALS ENCAPSULATED IN AN INORGANIC SHELL Centre National de la Recherche Scientifique - CNRS (FR) 2010-12-15 EP claimed
WO-2009125086-A1 FLUORESCENT NANOCRYSTALS ENCAPSULATED IN AN INORGANIC SHELL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- (FR) 2009-10-15 WO claimed
US-9958705-B2 Electro-active opthalmic lens having an optical power blending region E-VISION SMART OPTICS, INC. (US) 2018-05-01 US disclosed
US-20170307905-A1 Electro-Active Opthalmic Lens Having an Optical Power Blending Region E-VISION SMART OPTICS INC (US) 2017-10-26 US disclosed
US-9778489-B2 Electro-active spectacles E-VISION SMART OPTICS, INC. (US) 2017-10-03 US disclosed
US-20170010480-A1 Electro-Active Opthalmic Lens Having an Optical Power Blending Region E-VISION SMART OPTICS INC (US) 2017-01-12 US disclosed
US-20160363783-A1 Electro-Active Opthalmic Lens Having an Optical Power Blending Region E-VISION SMART OPTICS INC (US) 2016-12-15 US disclosed
US-9500883-B2 Electro-active opthalmic lens having an optical power blending region E-VISION SMART OPTICS, INC. (US) 2016-11-22 US disclosed
US-20160231593-A1 Electro-Active Opthalmic Lens Having an Optical Power Blending Region E-VISION SMART OPTICS INC (US) 2016-08-11 US disclosed
EP-1206720-A1 SYSTEM, APPARATUS, AND METHOD FOR CORRECTING VISION USING AN ELECTRO-ACTIVE LENS E-Vision, L.L.C. (US) 2002-05-22 EP disclosed
WO-2001001848-A1 METHOD FOR REFRACTING AND DISPENSING ELECTRO-ACTIVE SPECTACLES E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
WO-2001002895-A1 SYSTEM, APPARATUS, AND METHOD FOR CORRECTING VISION USING AN ELECTRO-ACTIVE LENS E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
WO-2001002897-A1 SYSTEM, APPARATUS, AND METHOD FOR CORRECTING VISION USING ELECTRO-ACTIVE SPECTACLES E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
WO-2001002896-A1 SYSTEM, APPARATUS, AND METHOD FOR REDUCING BIREFRINGENCE E-VISION, L.L.C. (US) 2001-01-11 WO disclosed
US-5496503-A DIOLS WITH AMINE GROUPS AND DOUBLE BOND, AZO OR IMINE GROUPS IN BACKBONE, POLYURETHANES, POLYESTERS NIPPON TELEGRAPH AND TELEPHONE (JP) 1996-03-05 US disclosed
US-5318729-A Polyurethane or polyester with chain interrupted by component having electron donor and pi-conjugated bonding groups NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-06-07 US disclosed