Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | KDM1A | O60341 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018983 | 0.81 | MEN1 (0.60) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL10313315 | 0.79 | MEN1 (0.49) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL13524798 | 0.78 | TOP2B (0.72) | MEN1KMT2AKDM1AMAPTSMN1; SMN2 | |
| SCHEMBL5107131 | 0.77 | MEN1 (0.73) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL12693676 | 0.77 | MAPT (0.62) | MEN1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL17423377 | 0.76 | KDM1A (0.64) | MEN1KMT2AGAAKDM1AMAPT | |
| SCHEMBL15673568 | 0.76 | KDM1A (1.00) | KMT2AKDM1AMAPTSMN1; SMN2LMNA | |
| SCHEMBL14116115 | 0.75 | KDM1A (0.68) | MEN1KMT2AGAAKDM1AMAPT | |
| SCHEMBL4906421 | 0.75 | KDM1A (0.58) | MEN1KMT2AGAAKDM1AMAPT | |
| SCHEMBL30307453 | 0.75 | RIPK2 (0.62) | MAPTSMN1; SMN2LMNANPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172292-A1 | METHOD FOR PROTECTION OF ANTIMICROBIAL AND ANTICANCER DRUGS FROM INACTIVATION BY NITRIC OXIDE | NEW YORK UNIVERSITY (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120172292-A1 | METHOD FOR PROTECTION OF ANTIMICROBIAL AND ANTICANCER DRUGS FROM INACTIVATION BY NITRIC OXIDE | NEW YORK UNIVERSITY (US) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172292-A1 | METHOD FOR PROTECTION OF ANTIMICROBIAL AND ANTICANCER DRUGS FROM INACTIVATION BY NITRIC OXIDE | NOS2, NOS1, NOS3 | MEN1 2416/4885KMT2A 3096/4885GAA 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.