Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LIPC | P11150 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031918 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1031541 | 0.78 | RAB9A (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1032676 | 0.74 | ADORA3 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1030582 | 0.73 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2LMNAPOLB | |
| SCHEMBL1030443 | 0.73 | RAB9A (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1032230 | 0.72 | ADORA3 (0.55) | ALDH1A1SMN1; SMN2LMNAUSP2POLB | |
| SCHEMBL1032651 | 0.72 | KMT2A (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL1030837 | 0.71 | NPC1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1032220 | 0.71 | RAB9A (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1031580 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |