Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031424 | 0.79 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KDM4EMAPTPOLB | |
| SCHEMBL1031918 | 0.76 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HPGDKDM4EMAPT | |
| SCHEMBL1030582 | 0.76 | MEN1 (0.47) | L3MBTL1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL1032220 | 0.75 | RAB9A (0.47) | ALDH1A1L3MBTL1HPGDKDM4EMAPT | |
| SCHEMBL1032676 | 0.75 | ADORA3 (0.49) | ALDH1A1L3MBTL1HPGDKDM4EMAPT | |
| SCHEMBL1032230 | 0.75 | ADORA3 (0.55) | ALDH1A1L3MBTL1HPGDKDM4EPOLB | |
| SCHEMBL1031541 | 0.74 | RAB9A (0.53) | ALDH1A1HPGDMAPTPOLBKMT2A | |
| SCHEMBL1030274 | 0.73 | POLB (0.46) | ALDH1A1L3MBTL1HPGDKDM4EMAPT | |
| SCHEMBL1033134 | 0.73 | P2RX7 (0.43) | SMN1; SMN2 | |
| SCHEMBL1475078 | 0.72 | NPC1 (0.72) | ALDH1A1L3MBTL1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |