Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843129 | 0.83 | PIK3CB (0.57) | PIK3CBMAPTKDM4ECHRNA7MEN1 | |
| Hydrochloric Acid SCHEMBL3850438 | 0.80 | PIK3CB (0.58) | PIK3CBMAPTKDM4ECHRNA7MEN1 | |
| SCHEMBL10314844 | 0.75 | XDH (0.37) | MAPTKDM4ETP53 | |
| SCHEMBL14151555 | 0.75 | KDM4E (0.48) | PIK3CBMAPTKDM4ECHRNA7MEN1 | |
| SCHEMBL10314921 | 0.73 | KDM4E (0.36) | MAPTKDM4EMEN1TP53CYP1A2 | |
| SCHEMBL10314834 | 0.71 | CHRNA7 (0.38) | PIK3CBKDM4ECHRNA7TUBB4ATUBB | |
| SCHEMBL14152235 | 0.70 | PIK3CB (0.45) | PIK3CBMAPTKDM4ECHRNA7MEN1 | |
| SCHEMBL30633549 | 0.69 | PIK3CB (0.51) | PIK3CBMAPTKDM4EMEN1TP53 | |
| SCHEMBL7914260 | 0.69 | PIK3CB (0.65) | PIK3CBMAPTKDM4ECHRNA7MEN1 | |
| SCHEMBL15242237 | 0.68 | PIK3CB (0.59) | PIK3CBMAPTKDM4ECHRNA7TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2532656-A1 | GPR119 AGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2012-12-12 | — | — | EP | disclosed |
| US-20120245344-A1 | GPR119 AGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2012-09-27 | — | — | US | disclosed |
| EP-2474540-A1 | GPR119 AGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2012-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245344-A1 | GPR119 AGONIST | GPR119, GPR4, GPR55 | PIK3CB 4112/4885MAPT 4861/4885KDM4E 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.