SCHEMBL10315679

SCHEMBL10315679

c1ccc(-c2ccc(-c3cccc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7ccc(N(c8ccccc8)c8ccccc8)cc7)c6c54)c3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ ATM Q13315 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ KMT2A Q03164 3/20 0.35
▸ IL1R1 P14778 1/20 0.35
▸ TSPO P30536 2/20 0.34
▸ HDAC4 P56524 1/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ HTT P42858 2/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ MAPT P10636 1/20 0.34
▸ FAAH O00519 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ MGLL Q99685 1/20 0.33
▸ OPRD1 P41143 2/20 0.33
▸ MAPK8 P45983 2/20 0.32
▸ HTR1A P08908 1/20 0.32
▸ HTR7 P34969 1/20 0.32
▸ GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10315682 1.00 L3MBTL1 (0.42) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL10315683 0.99 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL17539875 0.96 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL17539872 0.96 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL17539877 0.95 L3MBTL1 (0.46) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL22352551 0.94 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL31670 0.93 L3MBTL1 (0.49) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL10315685 0.92 L3MBTL1 (0.36) L3MBTL1ATMKDM4EKMT2ATSPO
SCHEMBL16675127 0.91 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AIL1R1
SCHEMBL10315678 0.91 L3MBTL1 (0.40) L3MBTL1ATMKDM4EKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450192-B2 Carbazole derivative and organic electroluminescent devices utilizing the same and fabrication method thereof E-RAY OPTOELECTRONICS TECHNOLOGY (TW) 2016-09-20 — — US disclosed
US-9450192-B2 Carbazole derivative and organic electroluminescent devices utilizing the same and fabrication method thereof E-RAY OPTOELECTRONICS TECHNOLOGY (TW) 2016-09-20 — — US disclosed
US-20120175598-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES UTILIZING THE SAME AND FABRICATION METHOD THEREOF E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2012-07-12 — — US disclosed
US-20120175598-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES UTILIZING THE SAME AND FABRICATION METHOD THEREOF E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2012-07-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120175598-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES UTILIZING THE SAME AND FABRICATION METHOD THEREOF AHR, ARNT, NAT1 L3MBTL1 2732/4885ATM 2102/4885KDM4E 2441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback