SCHEMBL10315685

SCHEMBL10315685

Cc1cccc(N(c2ccc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc(-c7ccc(-c8ccccc8)cc7)c6)c5c43)cc2)c2cccc(C)c2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ RXFP1 Q9HBX9 1/20 0.36
▸ OPRD1 P41143 2/20 0.35
▸ MAPT P10636 3/20 0.34
▸ TP53 P04637 2/20 0.34
▸ HSD17B1 P14061 1/20 0.34
▸ HSD17B2 P37059 1/20 0.34
▸ GAA P10253 2/20 0.33
▸ ALDH1A1 P00352 4/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ PER2 O15055 1/20 0.33
▸ CRY1 Q16526 1/20 0.33
▸ CRY2 Q49AN0 1/20 0.33
▸ TSPO P30536 1/20 0.33
▸ LMNA P02545 1/20 0.32
▸ PTGER4 P35408 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10315679 0.92 L3MBTL1 (0.42) L3MBTL1KDM4EATMOPRD1MAPT
SCHEMBL10315682 0.92 L3MBTL1 (0.42) L3MBTL1KDM4EATMOPRD1MAPT
SCHEMBL10315683 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMOPRD1MAPT
SCHEMBL15894186 0.89 KDM4E (0.44) L3MBTL1KDM4EATMRXFP1MAPT
SCHEMBL17539872 0.89 L3MBTL1 (0.44) L3MBTL1KDM4EATMOPRD1MAPT
SCHEMBL17539875 0.89 L3MBTL1 (0.44) L3MBTL1KDM4EATMOPRD1MAPT
SCHEMBL10315686 0.88 TSPO (0.39) L3MBTL1KDM4EATMRXFP1OPRD1
SCHEMBL17539877 0.87 L3MBTL1 (0.46) L3MBTL1KDM4EATMOPRD1MAPT
SCHEMBL10309964 0.86 KDM4E (0.43) L3MBTL1KDM4EATMRXFP1MAPT
SCHEMBL13803403 0.86 KDM4E (0.43) L3MBTL1KDM4EATMRXFP1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450192-B2 Carbazole derivative and organic electroluminescent devices utilizing the same and fabrication method thereof E-RAY OPTOELECTRONICS TECHNOLOGY (TW) 2016-09-20 — — US disclosed
US-9450192-B2 Carbazole derivative and organic electroluminescent devices utilizing the same and fabrication method thereof E-RAY OPTOELECTRONICS TECHNOLOGY (TW) 2016-09-20 — — US disclosed
US-20120175598-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES UTILIZING THE SAME AND FABRICATION METHOD THEREOF E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2012-07-12 — — US disclosed
US-20120175598-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES UTILIZING THE SAME AND FABRICATION METHOD THEREOF E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2012-07-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120175598-A1 CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICES UTILIZING THE SAME AND FABRICATION METHOD THEREOF AHR, ARNT, NAT1 L3MBTL1 2732/4885KDM4E 2441/4885ATM 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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