SCHEMBL10316366

SCHEMBL10316366

Cc1ccncc[nH]c2cccnc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
CCR1 P32246 3/20 0.38
CCR8 P51685 3/20 0.38
CCR5 P51681 2/20 0.38
PIK3CD O00329 1/20 0.37
MAPK14 Q16539 1/20 0.36
LMNA P02545 1/20 0.36
ATAD2 Q6PL18 1/20 0.36
CBFB Q13951 1/20 0.36
GRM4 Q14833 4/20 0.35
COPS5 Q92905 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL369216 0.76 PSMD14 (0.48) PSMD14L3MBTL1NPC1HSP90AA1ADORA3
Potassium SCHEMBL3219697 0.74 PSMD14 (0.47) PSMD14L3MBTL1NPC1HSP90AA1ADORA3
SCHEMBL3219684 0.74 PSMD14 (0.47) PSMD14L3MBTL1NPC1HSP90AA1ADORA3
SCHEMBL291660 0.67 PSMD14 (0.61) PSMD14HSP90AA1ADORA3ADORA2ACCR1
SCHEMBL8667 0.66 PARP1 (0.56) MGAMGAASIMGAM2CBFB
Hydrochloric Acid SCHEMBL28915576 0.64 PARP1 (0.55) MGAMGAASIMGAM2CBFB
SCHEMBL28215217 0.64 TDO2 (0.42) PSMD14L3MBTL1NPC1ADORA3ADORA2A
SCHEMBL1773094 0.63 PRMT5 (0.53) PSMD14L3MBTL1NPC1HSP90AA1CCR1
SCHEMBL12203219 0.62 CCR1 (0.65) PSMD14L3MBTL1NPC1HSP90AA1CCR1
SCHEMBL12396542 0.61 PARP1 (0.55) PSMD14HSP90AA1ADORA3ADORA2ACCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2475020-A1 ORGANIC ELECTROLUMINESCENT ELEMENT FUJIFILM Corporation (JP) 2012-07-11 EP disclosed