Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18418498 | 0.80 | PSMD14 (0.41) | TDO2KDRFLT3GSK3BPSMD14 | |
| SCHEMBL28214567 | 0.80 | PIM1 (0.50) | TDO2KDRFLT3GSK3BPSMD14 | |
| SCHEMBL369216 | 0.78 | PSMD14 (0.48) | TDO2KDRFLT3GSK3BPSMD14 | |
| SCHEMBL3219684 | 0.77 | PSMD14 (0.47) | TDO2KDRFLT3GSK3BPSMD14 | |
| Potassium SCHEMBL3219697 | 0.77 | PSMD14 (0.47) | TDO2KDRFLT3GSK3BPSMD14 | |
| SCHEMBL18418497 | 0.77 | COMT (0.49) | TDO2KDRFLT3GSK3BPSMD14 | |
| SCHEMBL17179382 | 0.75 | IMPDH2 (0.49) | KDRFLT3GSK3BPSMD14DYRK1A | |
| SCHEMBL28214631 | 0.74 | TDO2 (0.43) | TDO2KDRFLT3GSK3BPSMD14 | |
| SCHEMBL858410 | 0.73 | TGFBR1 (0.57) | FLT3GSK3BLRRK2DYRK1ACDK7 | |
| SCHEMBL29713628 | 0.73 | ATM (0.61) | PRKD3PRKD1NPC1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026094-A | Substituted 4-azaindoles and their use as modulators of the G L UN2B receptor | 詹森药业有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-108026094-A | Substituted 4-azaindoles and their use as modulators of the G L UN2B receptor | 詹森药业有限公司 | 2018-05-11 | — | — | CN | disclosed |