Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8794788 | 0.84 | HPGD (0.64) | HPGDMTNR1ANQO2SMN1; SMN2CYP1A2 | |
| SCHEMBL8590547 | 0.83 | MC5R (0.53) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5928598 | 0.81 | MC5R (0.51) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1491284 | 0.80 | MTNR1A (0.45) | HPGDMTNR1ANQO2CA12CA1 | |
| SCHEMBL15571660 | 0.78 | SIGMAR1 (0.51) | HPGDMTNR1ANQO2MEN1KMT2A | |
| SCHEMBL8858591 | 0.77 | NQO2 (0.58) | HPGDMTNR1ANQO2CYP1A2CYP2C9 | |
| SCHEMBL29891134 | 0.77 | CYP1A2 (0.48) | HPGDMTNR1ANQO2MEN1KMT2A | |
| SCHEMBL5516425 | 0.77 | CYP1A2 (0.48) | HPGDMTNR1ANQO2MEN1KMT2A | |
| SCHEMBL2572378 | 0.76 | TAAR1 (0.55) | HPGDMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL13086096 | 0.76 | MTNR1A (0.57) | HPGDMTNR1ANQO2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321451-B | Method for preparing cinacalcet hydrochloride drug intermediate | 福建海西新药创制有限公司 | 2022-08-23 | — | — | CN | disclosed |
| EP-2475641-A1 | PROCESS FOR PREPARING CINACALCET | ZaCh System S.p.A. (IT) | 2012-07-18 | — | — | EP | disclosed |