Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10316496 | 0.80 | HPGD (0.53) | MTNR1AHPGDNQO2CA2CA12 | |
| SCHEMBL15571660 | 0.75 | SIGMAR1 (0.51) | MTNR1AHPGDNQO2SIGMAR1 | |
| SCHEMBL8794788 | 0.74 | HPGD (0.64) | MTNR1AHPGDNQO2CA2CA12 | |
| SCHEMBL2361472 | 0.73 | CASR (0.43) | SIGMAR1 | |
| SCHEMBL18577920 | 0.70 | CTNNB1 (0.45) | MTNR1AHPGDCA2SIGMAR1SLC1A3 | |
| SCHEMBL4274577 | 0.70 | SIGMAR1 (0.47) | MTNR1AHPGDNQO2CA2CA12 | |
| SCHEMBL8858591 | 0.69 | NQO2 (0.58) | MTNR1AHPGDNQO2CA2CA12 | |
| SCHEMBL19553634 | 0.68 | MTNR1A (0.62) | MTNR1AHPGDNQO2CA2SIGMAR1 | |
| SCHEMBL13086096 | 0.67 | MTNR1A (0.57) | MTNR1AHPGDNQO2CA2CA12 | |
| SCHEMBL30736517 | 0.67 | MTNR1A (0.57) | MTNR1AHPGDNQO2CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029833-A1 | PROCESS FOR PREPARING CINACALCET | ZACH SYSTEM S.P.A. (IT) | 2011-03-17 | — | — | WO | disclosed |