SCHEMBL1031989

SCHEMBL1031989

Cc1cc(N=O)ccc1NC(C)CCC(C)C

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
RECQL P46063 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RAB9A P51151 1/20 0.33
GAA P10253 1/20 0.32
ALOX12 P18054 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1027890 0.81 NPC1 (0.31) NPC1ALDH1A1RAB9A
SCHEMBL7765530 0.77 ALDH1A1 (0.31) LMNANPC1ALDH1A1RAB9ANPSR1
SCHEMBL8372450 0.76 SIGMAR1 (0.42) LMNARECQLALDH1A1GAAP2RX7
SCHEMBL638296 0.76 ALDH1A1 (0.44) NPC1ALDH1A1RAB9AALOX12SMN1; SMN2
SCHEMBL6683632 0.71 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL26012913 0.71 ESR1 (0.37) LMNAALDH1A1GAANPSR1SMN1; SMN2
SCHEMBL1032197 0.70 ALDH1A1 (0.35) NPC1ALDH1A1RAB9AALOX12SMN1; SMN2
SCHEMBL1030258 0.70 SCN10A (0.34) NPC1ALDH1A1RAB9ANPSR1
SCHEMBL22648624 0.70 ALDH1A1 (0.38) LMNAALDH1A1
SCHEMBL27292055 0.67 TXNRD1 (0.35) ALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1474377-B1 NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS CHEMTURA CORP (US) 2011-01-19 EP claimed
US-7125475-B2 Nitrosophenols and C-nitrosoanilines as polymerization inhibitors CROMPTON CORPORATION (US) 2006-10-24 US claimed
EP-1474377-A1 NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS Crompton Corporation (US) 2004-11-10 EP claimed
WO-2003070687-A1 NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS CROMPTON CORPORATION (US) 2003-08-28 WO claimed
US-20030155227-A1 Nitrosophenols and C-nitrosoanilines as polymerization inhibitors CROMPTON CORPORATION 2003-08-21 US claimed
US-20180361319-A1 METHOD FOR IMPROVED REACTVE MONOMER PRODUCTION WITH MEMBRANE FILTRATION EVONIK DEGUSSA GMBH (DE) 2018-12-20 US disclosed
EP-2993164-B1 Phenolic (thio) acetals as inhibitors of the polymerisation of olefinically unsaturated monomers EVONIK DEGUSSA GMBH (DE) 2017-02-15 EP disclosed
EP-2993164-A1 Phenolic (thio) acetals as inhibitors of the polymerisation of olefinically unsaturated monomers Evonik Degussa GmbH (DE) 2016-03-09 EP disclosed
EP-1474377-B1 NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS CHEMTURA CORP (US) 2011-01-19 EP disclosed
US-7125475-B2 Nitrosophenols and C-nitrosoanilines as polymerization inhibitors CROMPTON CORPORATION (US) 2006-10-24 US disclosed
EP-1474377-A1 NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS Crompton Corporation (US) 2004-11-10 EP disclosed
WO-2003070687-A1 NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS CROMPTON CORPORATION (US) 2003-08-28 WO disclosed
US-20030155227-A1 Nitrosophenols and C-nitrosoanilines as polymerization inhibitors CROMPTON CORPORATION 2003-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180361319-A1 METHOD FOR IMPROVED REACTVE MONOMER PRODUCTION WITH MEMBRANE FILTRATION PUF60, MAX, SAMM50 LMNA 3213/4885RECQL 3482/4885NPC1 3917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.