Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 4/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689056 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL18609593 | 0.82 | MAPT (0.49) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL31454148 | 0.75 | ERN1 (0.56) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL17113788 | 0.75 | MAPT (0.54) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL4036164 | 0.75 | GPR35 (0.46) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL5213406 | 0.74 | ERN1 (0.59) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL10319978 | 0.74 | MAPK14 (0.44) | ALDH1A1MAPTCYP3A4TSHRTDP1 | |
| SCHEMBL18607573 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL24711757 | 0.71 | ALDH1A1 (0.48) | ALDH1A1MAPTCYP3A4TSHRTDP1 | |
| SCHEMBL28570533 | 0.71 | GPR35 (0.68) | ALDH1A1MAPTCYP3A4KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2484661-B1 | 2,3-DIHYDRO-1H-INDENE-2-YLUREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME | TORAY INDUSTRIES (JP) | 2017-04-26 | — | — | EP | disclosed |
| US-8653304-B2 | 2,3-dihydro-1H-indene-2-yl urea derivative and pharmaceutical application of same | TORAY INDUSTRIES, INC. (JP) | 2014-02-18 | — | — | US | disclosed |
| EP-2484661-A1 | 2,3-DIHYDRO-1H-INDENE-2-YLUREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME | Toray Industries, Inc. (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120184735-A1 | 2,3-DIHYDRO-1H-INDENE-2-YL UREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME | TORAY INDUSTRIES, INC. (JP) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184735-A1 | 2,3-DIHYDRO-1H-INDENE-2-YL UREA DERIVATIVE AND PHARMACEUTICAL APPLICATION OF SAME | SLC14A1, UROD, UGP2 | ALDH1A1 223/4885MAPT 466/4885CYP3A4 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.