SCHEMBL11528615

SCHEMBL11528615

CCCc1ccc(C(=O)c2ccccc2F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.59
NPC1 O15118 4/20 0.59
RAB9A P51151 4/20 0.59
PLK1 P53350 1/20 0.51
POLB P06746 4/20 0.51
CTDSP1 Q9GZU7 3/20 0.51
KMT2A Q03164 1/20 0.51
MCOLN3 Q8TDD5 1/20 0.51
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48
ALDH1A1 P00352 2/20 0.48
LMNA P02545 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ABCC9 O60706 1/20 0.47
ABCC8 Q09428 1/20 0.47
KCNJ11 Q14654 1/20 0.47
KCNJ8 Q15842 1/20 0.47
THRB P10828 1/20 0.46
DPP4 P27487 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10322210 0.91 PLK1 (0.54) GAANPC1RAB9APLK1ALDH1A1
SCHEMBL11530894 0.89 PLK1 (0.52) GAANPC1RAB9APLK1KMT2A
SCHEMBL10759830 0.82 CES2 (0.62) GAANPC1RAB9AKMT2AALDH1A1
SCHEMBL28013663 0.82 AKR1C3 (0.62) NPC1RAB9APLK1POLBCTDSP1
SCHEMBL8074361 0.81 GAA (0.52) GAANPC1RAB9APLK1POLB
Benzophenone SCHEMBL28417175 0.79 L3MBTL1 (0.58) GAANPC1RAB9APLK1POLB
SCHEMBL4605419 0.79 L3MBTL1 (0.58) GAANPC1RAB9APLK1POLB
SCHEMBL9861628 0.78 PLK1 (0.64) GAANPC1RAB9APLK1POLB
SCHEMBL5973730 0.78 MAPK14 (0.46) GAANPC1RAB9APOLBCTDSP1
SCHEMBL1630752 0.78 AKR1C3 (0.65) GAANPC1RAB9APOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4145444-A 4-BUTYL-BENZOPHENONE KAKEN CHEMICAL CO., LTD. (JP) 1979-03-20 US disclosed
US-4124726-A 2-FLUORO-4'-ALKYLBENZOPHENONE KAKEN CHEMICAL CO., LTD. (JP) 1978-11-07 US disclosed