SCHEMBL1032225

SCHEMBL1032225

CCCN(CCCN1CCOCC1)CCCN1CCOCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
KEAP1 Q14145 1/20 0.48
ALDH1A1 P00352 4/20 0.47
SIGMAR1 Q99720 3/20 0.47
MAPK1 P28482 2/20 0.47
CYP1A2 P05177 2/20 0.47
CHRM2 P08172 1/20 0.47
CHRM1 P11229 1/20 0.47
HTR2A P28223 1/20 0.47
SCN1A P35498 1/20 0.47
HTR2B P41595 1/20 0.47
KCNH2 Q12809 1/20 0.47
SCN2A Q99250 1/20 0.47
SCN3A Q9NY46 1/20 0.47
HRH3 Q9Y5N1 1/20 0.47
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
DRD3 P35462 1/20 0.42
HPGD P15428 1/20 0.41
DUSP3 P51452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883021 1.00 SMN1; SMN2 (0.48) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1
SCHEMBL5911029 0.90 KEAP1 (0.58) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1
SCHEMBL1032529 0.86 KEAP1 (0.50) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1
SCHEMBL1133412 0.86 KEAP1 (0.50) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1
SCHEMBL9705617 0.82 ALDH1A1 (0.46) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1
SCHEMBL23223379 0.81 SIGMAR1 (0.40) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1
SCHEMBL10899230 0.81 ALDH1A1 (0.53) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1
SCHEMBL84935 0.79 ALDH1A1 (0.61) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1
SCHEMBL12228117 0.78 SMN1; SMN2 (0.46) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1
SCHEMBL1033434 0.78 KEAP1 (0.54) SMN1; SMN2KEAP1ALDH1A1SIGMAR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4214256-B1 LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES LANXESS CORP (US) 2024-09-11 EP disclosed
US-20230383157-A1 LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES LANXESS CORPORATION (US) 2023-11-30 US disclosed
EP-4214256-A1 LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES LANXESS Corporation (US) 2023-07-26 EP disclosed
WO-2022061087-A1 LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES LANXESS CORPORATION (US) 2022-03-24 WO disclosed
US-10626392-B2 Particulate solid composite material for nucleic acid purification, containing magnetic nanoparticles AXAGARIUS GMBH & CO. KG (DE) 2020-04-21 US disclosed
EP-2531544-B1 POLYETHER BLOCK COPOLYMERS AND COMPOSITIONS THAT CAN BE OBTAINED THEREFROM HENKEL AG & CO KGAA (DE) 2018-10-17 EP disclosed
EP-2546278-B1 Polyether block copolymers and the compositions resulting from these HENKEL AG & CO KGAA (DE) 2018-08-22 EP disclosed
EP-3321300-A1 PARTICULATE SOLID COMPOSITE MATERIAL FOR NUCLEIC ACID PURIFICATION COMPRISING MAGNETIC NANOPARTICLES AXAGARIUS GmbH & Co. KG (DE) 2018-05-16 EP disclosed
US-20180127742-A1 PARTICULATE SOLID COMPOSITE MATERIAL FOR NUCLEIC ACID PURIFICATION, CONTAINING MAGNETIC NANOPARTICLES AXAGARIUS GMBH & CO. KG (DE) 2018-05-10 US disclosed
EP-3230332-A1 BREATHABLE POLYURETHANE HOTMELT ADHESIVE Sika Technology AG (CH) 2017-10-18 EP disclosed
WO-2003006521-A1 REACTIVE POLYURETHANES HAVING A REDUCED DIISOCYANATE MONOMERS CONTENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-01-23 WO disclosed
WO-2003002683-A1 ADHESIVE/ WATERTIGHT MATERIAL WITH HIGH ELECTRICAL RESISTANCE HENKEL TEROSON GMBH (DE) 2003-01-09 WO disclosed
EP-1250394-A1 POLYURETHANE COMPOSITIONS ON THE BASIS OF POLYESTER-POLYETHER COPOLYMERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-10-23 EP disclosed
EP-1237971-A1 ADHESION PROMOTERS FOR MONOMER-FREE REACTIVE POLYURETHANES Henkel Kommanditgesellschaft auf Aktien (DE) 2002-09-11 EP disclosed
WO-2001096436-A1 POLYURETHANE COMPOSITIONS BASED ON POLYESTER BLOCK COPOLYMERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-20 WO disclosed
WO-2001046330-A1 POLYURETHANE COMPOSITIONS ON THE BASIS OF POLYESTER-POLYETHER COPOLYMERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-06-28 WO disclosed
WO-2001040342-A1 ADHESION PROMOTERS FOR MONOMER-FREE REACTIVE POLYURETHANES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-06-07 WO disclosed
EP-0054219-B1 PROCESS FOR THE PRODUCTION OF FOAMED POLYURETHANES BAYER AG (DE) 1986-02-26 EP disclosed
US-4379861-A Process for the production of polyurethanes using morpholine compounds as catalysts BAYER AKTIENGESELLSCHAFT (DE) 1983-04-12 US disclosed
EP-0054219-A1 Process for the production of foamed polyurethanes BAYER AG (DE) 1982-06-23 EP disclosed