SCHEMBL10322397

SCHEMBL10322397

Cc1ccc(CNC(=O)N(Cc2ccccc2)C2CCNCC2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.58
DCUN1D1 Q96GG9 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
SLC6A2 P23975 4/20 0.49
SLC6A4 P31645 4/20 0.49
SLC6A3 Q01959 2/20 0.49
KCNH2 Q12809 1/20 0.47
UBE2M P61081 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
PKM P14618 1/20 0.47
CYP2C19 P33261 1/20 0.47
GAA P10253 1/20 0.46
CCR5 P51681 1/20 0.45
OPRM1 P35372 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL340564 1.00 HTR2A (0.58) HTR2ADCUN1D1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL16118655 0.93 HTR2A (0.59) HTR2ADCUN1D1ALDH1A1KDM4EUSP2
SCHEMBL5329449 0.85 HTR2A (0.59) HTR2ADCUN1D1SLC6A2SLC6A3KCNH2
SCHEMBL340169 0.85 HTR2A (0.59) HTR2ADCUN1D1SLC6A2SLC6A3KCNH2
SCHEMBL4211121 0.83 OPRM1 (0.61) DCUN1D1UBE2MCCR5OPRM1
SCHEMBL7091708 0.83 OPRM1 (0.61) DCUN1D1UBE2MCCR5OPRM1
Hydrochloric Acid SCHEMBL4207721 0.82 OPRM1 (0.60) DCUN1D1UBE2MCCR5OPRM1
SCHEMBL341661 0.82 CTSD (0.56) DCUN1D1SLC6A2SLC6A4SLC6A3KCNH2
Oxalic Acid SCHEMBL4208908 0.81 OPRM1 (0.59) DCUN1D1ALDH1A1KDM4EUBE2MPKM
SCHEMBL6633233 0.81 DCUN1D1 (0.60) HTR2ADCUN1D1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120183600-A1 NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS CHEN CHIEN-HUNG (US) 2012-07-19 US disclosed