SCHEMBL112084

SCHEMBL112084

CC1CCC(C(C)C)C(C(C)(O)C(=O)O)C1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.47
TRPM8 Q7Z2W7 5/20 0.46
TRPA1 O75762 2/20 0.46
TRPV1 Q8NER1 4/20 0.45
KCNA5 P22460 1/20 0.40
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactic Acid SCHEMBL31239678 0.94 EPHX1 (0.43) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL9951821 0.85 EPHX1 (0.49) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL1032282 0.85 EPHX1 (0.49) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL30460652 0.84 EPHX1 (0.44) EPHX1ALDH1A1HPGD
SCHEMBL29018734 0.83 EPHX1 (0.47) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL29449500 0.81 TRPM8 (0.49) EPHX1TRPM8TRPV1KCNA5ALDH1A1
SCHEMBL18280697 0.80 EPHX1 (0.44) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL29393944 0.79 EPHX1 (0.50) EPHX1TRPV1ALDH1A1HPGD
SCHEMBL9950972 0.79 EPHX1 (0.46) EPHX1TRPM8TRPA1TRPV1KCNA5
SCHEMBL11211108 0.79 EPHX1 (0.50) EPHX1TRPM8TRPA1TRPV1KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3817575-A1 SOLUBILIZATION OF POORLY SOLUBLE COOLING SUBSTANCES Symrise AG (DE) 2021-05-12 EP claimed
WO-2020007484-A1 SOLUBILIZATION OF POORLY SOLUBLE COOLING SUBSTANCES SYMRISE AG (DE) 2020-01-09 WO claimed
US-20080213248-A1 Methods and Systems for Treating Asthma and Other Respiratory Diseases UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-09-04 US claimed
US-20070190190-A1 Conditioning compositions and methods of use thereof JR CHEM, LLC 2007-08-16 US claimed
US-6660304-B2 Method of treating prickly heat JOHNSON & JOHNSON CONSUMER COMPANIES, INC 2003-12-09 US claimed
US-6048549-A Powder compositions JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2000-04-11 US claimed
CN-117202986-A Hydrogel encapsulation and method for producing same 国际香精香料公司 2023-12-08 CN disclosed
EP-4209264-A1 MICROCAPSULE COMPOSITIONS STABILIZED WITH VISCOSITY CONTROL AGENTS International Flavors & Fragrances Inc. (US) 2023-07-12 EP disclosed
WO-2022252663-A1 USE OF COMPOSITION OF ALCOHOL AND COOLING AGENT IN REGULATING SEXUAL FUNCTION, PROTECTING CARDIOVASCULAR AND CEREBROVASCULAR SYSTEM, PROMOTING HEPATOCYTE REGENERATION, FIGHTING AGAINST TUMOR, AND IMPROVING IMMUNITY AND SLEEP QUALITY 青海春天药用资源科技股份有限公司 2022-12-08 WO disclosed
EP-3817575-A1 SOLUBILIZATION OF POORLY SOLUBLE COOLING SUBSTANCES Symrise AG (DE) 2021-05-12 EP disclosed
US-10980727-B2 Mixtures containing (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide SYMRISE AG (DE) 2021-04-20 US disclosed
EP-3787904-A1 SYSTEM AND METHOD FOR PRINTING AND DRYING FLAVORS AND FRAGRANCES International Flavors & Fragrances Inc. (US) 2021-03-10 EP disclosed
CN-107460766-B Mint cigarette paper with moisture retention function and preparation method thereof 河南中烟工业有限责任公司 2020-11-17 CN disclosed
US-7173146-B1 Menthyl lactate process MILLENNIUM SPECIALTY CHEMICALS, INC. (US) 2007-02-06 US disclosed
WO-2006007751-A2 METABOLIC METHOD TO IDENTIFY FLAVOURS AND/OR FRAGRANCES GIVAUDAN SA (CH) 2006-01-26 WO disclosed
CN-1571765-A Esters of aromatic alkoxylated alcohols and fatty carboxylic acids CRODA INC (US) 2005-01-26 CN disclosed
US-6426092-B1 Powder compositions comprising a skin irritation reducing agent JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2002-07-30 US disclosed
JP-2000273036-A LIQUID FORMULATION HAVING MASKED BITTERNESS KOBAYASHI PHARMACEUT CO LTD 2000-10-03 JP disclosed
CN-1209056-A Stable topical compositions PROCTER & GAMBLE (US) 1999-02-24 CN disclosed
WO-1998007404-A1 AQUEOUS SKIN COSMETIC COMPOSITION CONTAINING A WATER-INSOLUBLE POWDER KAO CORPORATION (JP) 1998-02-26 WO disclosed