Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18280697 | 0.84 | EPHX1 (0.44) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| Bicarbonate SCHEMBL29029158 | 0.83 | EPHX1 (0.45) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL9951821 | 0.80 | EPHX1 (0.49) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL1032282 | 0.80 | EPHX1 (0.49) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL112084 | 0.79 | EPHX1 (0.47) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL29018734 | 0.79 | EPHX1 (0.47) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL5981079 | 0.78 | TRPM8 (0.48) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL19809105 | 0.78 | TRPM8 (0.44) | EPHX1TRPM8TRPA1TRPV1CYP19A1 | |
| SCHEMBL15282238 | 0.77 | EPHX1 (0.43) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL7214058 | 0.76 | EPHX1 (0.45) | EPHX1TRPM8TRPA1KCNA5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165559-A1 | Compounds Having a Physiological Effect | V. MANE FILS (FR) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165559-A1 | Compounds Having a Physiological Effect | NPPA, CYP11B2, SHBG | EPHX1 871/4885TRPM8 412/4885TRPA1 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.