Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559030 | 0.77 | TSHR (0.50) | SIGMAR1TAAR1SLC18A2TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL3555371 | 0.76 | TSHR (0.48) | SIGMAR1TAAR1SLC18A2TSHRKMT2A | |
| SCHEMBL28065470 | 0.76 | LTA4H (0.39) | TAAR1TSHRIDO1KMT2ANPC1 | |
| SCHEMBL28027281 | 0.73 | TSHR (0.36) | SIGMAR1TAAR1SLC18A2TSHRIDO1 | |
| SCHEMBL25589819 | 0.70 | SIGMAR1 (0.68) | SIGMAR1TAAR1SLC18A2TSHRCYP1A2 | |
| SCHEMBL5072576 | 0.70 | SIGMAR1 (0.68) | SIGMAR1TAAR1SLC18A2TSHRCYP1A2 | |
| SCHEMBL9637850 | 0.70 | TSHR (0.48) | TSHRCYP1A2IDO1 | |
| SCHEMBL5072573 | 0.70 | SIGMAR1 (0.68) | SIGMAR1TAAR1SLC18A2TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL3550627 | 0.70 | TSHR (0.45) | SIGMAR1TAAR1SLC18A2TSHRBCHE | |
| Hydrochloric Acid SCHEMBL7037524 | 0.69 | SIGMAR1 (0.66) | SIGMAR1TAAR1SLC18A2TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4363425-A1 | SMARCA DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023278402-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2014014845-A1 | COMBINATION THERAPY COMPRISING|1 -ETHYL-3-[5-[2-{1 -HYDROXY-1 -METHYL-ETHYL}PYRIMIDIN-5-YL]-7-(TETRA HYDROFURAN-2-|YL}-1 H-BENZIMIDAZOL-2-YL]UREA AND DERIVATIVES THEREOF TO TREAT MYCOBACTERIUM|DISEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-01-23 | — | — | WO | disclosed |
| EP-2663557-A1 | PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS | Vertex Pharmaceuticals Incorporated (US) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012097269-A1 | PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-07-19 | — | — | WO | disclosed |