Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1450921 | 0.88 | TSHR (0.46) | TSHRALDH1A1HTR1AADRA1DADRA1A | |
| SCHEMBL28065470 | 0.79 | LTA4H (0.39) | TSHRALDH1A1LMNAIDO1TAAR1 | |
| SCHEMBL194803 | 0.78 | TSHR (0.57) | TSHRALDH1A1LMNAL3MBTL1IDO1 | |
| SCHEMBL27599992 | 0.78 | TDP1 (0.44) | LMNA | |
| Phosphine SCHEMBL21501010 | 0.77 | TSHR (0.40) | TSHRALDH1A1HTR1AADRA1DADRA1A | |
| SCHEMBL11687302 | 0.75 | TSHR (0.55) | TSHRALDH1A1LMNAL3MBTL1IDO1 | |
| Bromide SCHEMBL11675628 | 0.73 | TSHR (0.52) | TSHRALDH1A1LMNAL3MBTL1IDO1 | |
| SCHEMBL10325280 | 0.73 | SIGMAR1 (0.38) | TSHRSIGMAR1IDO1TAAR1SLC18A2 | |
| SCHEMBL18544225 | 0.73 | TSHR (0.43) | TSHRALDH1A1SIGMAR1LMNAL3MBTL1 | |
| SCHEMBL24862583 | 0.72 | L3MBTL1 (0.36) | TSHRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817592-A | Water-soluble derivatives and prodrugs of acacetin and methods of making and using same | VERSITECH LTD | 2015-08-05 | — | — | CN | disclosed |