SCHEMBL10325656

SCHEMBL10325656

CCC(c1ccccc1)C(C)(CC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
ESR1 P03372 1/20 0.40
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 1/20 0.39
BCL2L1 Q07817 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
BCL2L2 Q92843 1/20 0.39
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
RIPK1 Q13546 3/20 0.36
KCNN4 O15554 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
KCNA5 P22460 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9082488 0.90 ESR1 (0.40) ESR1MEN1ALDH1A1KMT2ABCL2L1
SCHEMBL9077582 0.80 LMNA (0.43) LMNAMEN1KMT2ACYP1A2CYP3A4
SCHEMBL1176305 0.80 LMNA (0.43) LMNAMEN1KMT2ACYP1A2CYP3A4
SCHEMBL756001 0.78 LMNA (0.42) LMNAMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL753994 0.78 RIPK1 (0.41) LMNAESR1TAAR1RIPK1KCNN4
SCHEMBL28248384 0.78 LMNA (0.45) LMNAMEN1KMT2ACYP1A2CYP3A4
SCHEMBL9064416 0.78 TAAR1 (0.40) LMNAESR1MEN1ALDH1A1KMT2A
SCHEMBL756292 0.78 LMNA (0.45) LMNAMEN1KMT2ACYP1A2CYP3A4
SCHEMBL29010468 0.77 LMNA (0.48) LMNACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL11588095 0.76 LMNA (0.43) LMNAMEN1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2663594-B1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-26 EP claimed
CN-103415564-B For the anti-oxidant compounds of polyolefin resin DOW GLOBAL TECHNOLOGIES LLC (US) 2016-04-13 CN claimed
EP-2663594-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS Dow Global Technologies LLC (US) 2013-11-20 EP claimed
US-20130287985-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DEMIRORS MEHMET (US) 2013-10-31 US claimed
WO-2012096962-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-07-19 WO claimed
EP-2663594-B1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-26 EP disclosed
CN-103415564-B For the anti-oxidant compounds of polyolefin resin DOW GLOBAL TECHNOLOGIES LLC (US) 2016-04-13 CN disclosed
EP-2663594-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS Dow Global Technologies LLC (US) 2013-11-20 EP disclosed
US-20130287985-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DEMIRORS MEHMET (US) 2013-10-31 US disclosed
WO-2012096962-A1 ANTIOXIDANT COMPOUNDS FOR POLYOLEFIN RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-07-19 WO disclosed