Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17241923 | 0.82 | POLB (0.39) | LMNARIPK1MEN1KMT2ANPC1 | |
| SCHEMBL756292 | 0.79 | LMNA (0.45) | LMNARIPK1KCNN4MIFCYP1A2 | |
| SCHEMBL28248384 | 0.79 | LMNA (0.45) | LMNARIPK1KCNN4MIFCYP1A2 | |
| SCHEMBL10325656 | 0.78 | LMNA (0.41) | LMNARIPK1KCNN4MIFCYP1A2 | |
| SCHEMBL11588095 | 0.78 | LMNA (0.43) | LMNARIPK1KCNN4MIFCYP1A2 | |
| SCHEMBL1176305 | 0.78 | LMNA (0.43) | LMNARIPK1KCNN4MIFCYP1A2 | |
| Phosphine SCHEMBL10951511 | 0.78 | LMNA (0.43) | LMNARIPK1KCNN4MIFCYP1A2 | |
| SCHEMBL11590303 | 0.78 | LMNA (0.43) | LMNARIPK1KCNN4MIFCYP1A2 | |
| SCHEMBL9077582 | 0.78 | LMNA (0.43) | LMNARIPK1KCNN4MIFCYP1A2 | |
| SCHEMBL16685441 | 0.77 | MEN1 (0.48) | LMNAMEN1KMT2ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605207-B2 | Heat resistance; using with polystyrene fthermoplastic foams | BROMINE COMPOUNDS LTD. (IL) | 2009-10-20 | — | — | US | claimed |
| US-20080281024-A1 | Flame Retardant Bromobenzyl Systems | BROMINE COMPOUNDS LTD. (IL) | 2008-11-13 | — | — | US | claimed |
| EP-1951798-A2 | FLAME RETARDANT BROMOBENZYL SYSTEMS | Bromine Compounds Ltd. (IL) | 2008-08-06 | — | — | EP | claimed |
| WO-2007057900-A2 | FLAME RETARDANT BROMOBENZYL SYSTEMS | BROMINE COMPOUNDS LTD. (IL) | 2007-05-24 | — | — | WO | claimed |
| EP-2284196-B1 | Process for the preparation of expandable vinyl aromatic polymers with a reduced thermal conductivity by polymerization in suspension | POLIMERI EUROPA SPA (IT) | 2012-03-21 | — | — | EP | disclosed |
| EP-2284196-A1 | Process for the preparation of expandable vinyl aromatic polymers with a reduced thermal conductivity by polymerization in suspension | Polimeri Europa S.p.A. (IT) | 2011-02-16 | — | — | EP | disclosed |
| US-7605207-B2 | Heat resistance; using with polystyrene fthermoplastic foams | BROMINE COMPOUNDS LTD. (IL) | 2009-10-20 | — | — | US | disclosed |
| US-7585912-B2 | Flame-retardant polystyrenes | BROMINE COMPOUNDS LTD. (IL) | 2009-09-08 | — | — | US | disclosed |
| EP-1786853-B1 | NOVEL FLAME-RETARDANT POLYSTYRENES | BROMINE COMPOUNDS LTD (IL) | 2009-04-15 | — | — | EP | disclosed |
| US-20080281024-A1 | Flame Retardant Bromobenzyl Systems | BROMINE COMPOUNDS LTD. (IL) | 2008-11-13 | — | — | US | disclosed |
| EP-1951798-A2 | FLAME RETARDANT BROMOBENZYL SYSTEMS | Bromine Compounds Ltd. (IL) | 2008-08-06 | — | — | EP | disclosed |
| US-20070257241-A1 | Novel Flame-Retardant Polystyrenes | BROMINE COMPOUNDS LTD. (IL) | 2007-11-08 | — | — | US | disclosed |
| WO-2007057900-A2 | FLAME RETARDANT BROMOBENZYL SYSTEMS | BROMINE COMPOUNDS LTD. (IL) | 2007-05-24 | — | — | WO | disclosed |
| EP-1786853-A1 | NOVEL FLAME-RETARDANT POLYSTYRENES | Bromine Compounds Ltd. (IL) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006013554-A1 | NOVEL FLAME-RETARDANT POLYSTYRENES | BROMINE COMPOUNDS LTD. (IL) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080281024-A1 | Flame Retardant Bromobenzyl Systems | PBRM1, PFAS, BPTF | LMNA 738/4885RIPK1 4057/4885KCNN4 4675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.